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Brief Title: Study of Lenvatinib w/ Pembro in Black Participants w/Mismatch Repair-Prof Recurrent Endometrial Cancer
Official Title: A Multicenter, Open-Label Phase 2 Study to Evaluate the Safety and Efficacy of Lenvatinib in Combination With Pembrolizumab in Black Participants With Mismatch Repair-Proficient Recurrent Endometrial Cancer
Study ID: NCT05263492
Brief Summary: Determine the efficacy of the combination of lenvatinib and pembrolizumab in Black participants
Detailed Description: This study is a single-arm, open-label, multicenter phase 2 trial designed to prospectively evaluate the safety and efficacy of lenvatinib in combination with pembrolizumab for mismatch repair proficient recurrent endometrial cancer in Black patients (a population under-represented on 2 FDA registration trials).
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Virginia Commonwealth University, Richmond, Virginia, United States
Name: Leslie Randall, MD
Affiliation: Massey Cancer Center
Role: PRINCIPAL_INVESTIGATOR