Spots Global Cancer Trial Database for Safety and Efficacy of Retifanlimab (INCMGA00012) Alone or in Combination With Other Therapies in Participants With Advanced or Metastatic Endometrial Cancer Who Have Progressed on or After Platinum-based Chemotherapy.
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Trial Identification
Brief Title: Safety and Efficacy of Retifanlimab (INCMGA00012) Alone or in Combination With Other Therapies in Participants With Advanced or Metastatic Endometrial Cancer Who Have Progressed on or After Platinum-based Chemotherapy.
Official Title: An Umbrella Study of INCMGA00012 Alone and in Combination With Other Therapies in Participants With Advanced or Metastatic Endometrial Cancer Who Have Progressed on or After Platinum-Based Chemotherapy (POD1UM-204)
Study ID: NCT04463771
Conditions
Study Description
Brief Summary: This is a multicenter, open-label, nonrandomized, Phase 2 umbrella study of retifanlimab in participants who have advanced or metastatic endometrial cancer that has progressed on or after platinum-based chemotherapy. retifanlimab will be administered as monotherapy or in combination with other immunotherapy or targeted agents.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Alaska Womens Cancer Care Akwcc, Anchorage, Alaska, United States
Honorhealth, Phoenix, Arizona, United States
Arizona Oncology Associates, Tucson, Arizona, United States
UCLA Medical Hematology & Oncology, Los Angeles, California, United States
Olive View Med Ctr, Sylmar, California, United States
Broward Health Medical Center, Fort Lauderdale, Florida, United States
Mount Sinai Medical Center Comprehensive Cancer Center, Miami Beach, Florida, United States
Miami Cancer Institute, Miami, Florida, United States
Advent Health Medical Group-Orlando 2501, Orlando, Florida, United States
H. Lee Moffitt Cancer Center and Research Institute Hospital, Tampa, Florida, United States
Georgia Cancer Center, Augusta, Georgia, United States
Barbara Ann Karmanos Cancer Hospital, Detroit, Michigan, United States
Minnesota Oncology-Maplewood, Minneapolis, Minnesota, United States
Midwest Cancer Care, Kansas City, Missouri, United States
Washington University, Saint Louis, Missouri, United States
Billings Clinic Cancer Center, Billings, Montana, United States
Comprehensive Cancer Centers of Nevada, Henderson, Nevada, United States
New Mexico Cancer Care Alliance, Albuquerque, New Mexico, United States
Laura & Isaac Perlmutter Cancer Ctr, New York, New York, United States
University of North Carolina At Chapel Hill, Chapel Hill, North Carolina, United States
The Ohio State University Wexner Medical Center Division of Gynecologic Oncology, Hilliard, Ohio, United States
Willamette Valley Cancer Institute, Eugene, Oregon, United States
Texas Oncology-Tyler, Sioux Falls, South Dakota, United States
Tennessee Oncology, Nashville, Tennessee, United States
Texas Oncology-Austin Center, Austin, Texas, United States
Texas Oncology-Fort Worth South Henderson, Fort Worth, Texas, United States
Texas Oncology San Antonio, San Antonio, Texas, United States
Texas Oncology the Woodlands, Shenandoah, Texas, United States
Virginia Commonwealth University, Richmond, Virginia, United States
O.L.V Ziekenhuis, Aalst, , Belgium
Institut Jules Bordet, Brussels, , Belgium
Ghent University Hospital, Gent, , Belgium
Universitaire Ziekenhuis Leuven - Gasthuisberg, Leuven, , Belgium
Centre Hospitalier Universitaire de Liege - Sart Tilman, Liège, , Belgium
Chu Ucl Namur de Saint Elisabeth, Namur, , Belgium
The Affiliated Drum Tower Hospital of Nanjing University, Nanjing, , China
Chu Besancon Hospital Jean Minjoz, Besancon, , France
Institut Bergonie, Bordeaux Cedex, , France
Hospital Cochin Cancerologie, Paris, , France
Cario - Centre Armoricain de Radiotherapie Imagerie Medicale Et Oncologie, Plérin, , France
Centre de Lutte Contre Le Cancer - Institut de Cancerologie de L'Ouest - Rene Gauducheau, Saint Herblain, , France
Institut Gustave Roussy, Villejuif Cedex, , France
High Technology Hospital Medcenter, Batumi, , Georgia
Jsc Evex Hospitals, Kutaisi, , Georgia
Todua Clinic, Llc, Tbilisi, , Georgia
Caucasus Medical Centre Llc, Tbilisi, , Georgia
INNOVA, Tbilisi, , Georgia
Multiprofile Clinic Consilium Medulla Llc, Tbilisi, , Georgia
Charite - Campus Virchow-Klinikum, Berlin, , Germany
University Clinic Carl Gustav Carus Technical University Dresden, Dresden, , Germany
Klinikum Kassel Gmbh, Kassel, , Germany
Universitarsfrauenklinik Ulm, ULM, , Germany
Alexandra General Hospital of Athens, Athens, , Greece
University Hospital of West Attica - Attikon, Athens, , Greece
Hygeia Hospital, Marousi, , Greece
Euromedica General Clinic of Thessaloniki, Thessaloniki, , Greece
Azienda Ospedaliero-Universitaria Di Bologna Policlinico S. Orsola - Malpighi, Bologna, , Italy
Presidio Ospedaliero Di Summa Antonio Perrino, Brindisi, , Italy
Istituto Scientifico Romagnolo Per Lo Studio E La Cura Dei Tumori, Meldola, , Italy
Istituto Di Ricovero E Cura A Carattere Scientifico (Irccs) Ospedale San Raffaele, Milano, , Italy
Comitato Etico Fondazione Irccs Istituto Nazionale Dei Tumori Milano, Milano, , Italy
European Institute of Oncology, Milano, , Italy
Istituto Nazionale Tumori Irccs Fondazione Pascale, Napoli, , Italy
Iov - Istituto Oncologico Veneto Irccs, Padova, , Italy
Fondazione Policlinico Universitario Agostino Gemelli Irccs, Roma, , Italy
Ospedale Santa Maria Ca Foncello, Treviso, , Italy
Contact Details
Name: Mark Cornfield
Affiliation: Incyte Corporation
Role: STUDY_DIRECTOR
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