Spots Global Cancer Trial Database for Role of Senescence in the Development of Endometrial Cancer
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Trial Identification
Brief Title: Role of Senescence in the Development of Endometrial Cancer
Official Title: Role of Senescence in the Development of Endometrial Cancer
Study ID: NCT03338985
Interventions
Study Description
Brief Summary: Several molecular studies showed chromosomal alterations in patients with endometrial cancer, with gains in 1q, 19p, 19q, 8q, 10q and 10p and loss of 4q, 16q and 18q. Several genes of interest have been identified (P53, PTEN, PIK3CA, ß-catenin, K-ras ...). A study has already been carried out at the Reims University Hospital with inclusion of patients with endometrial cancer and patients with endometrial hyperplasia. It identified specific alterations of nosologic continuum of pathology and characterize areas of interest on the genome.
Detailed Description: make a pangenomic investigation of genetic abnormalities in atypical endometrial hyperplasia and endometrial cancers.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Damien JOLLY, Reims, , France
Contact Details
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