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Brief Title: A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1195, in 18- to 55-Year-Old Healthy Adults
Official Title: A Phase 1, Randomized, Observer-Blind, Placebo-Controlled, 2-Part, Dose-Ranging Study of an EBV Candidate Vaccine, mRNA-1195, in Healthy Adults 18 to 55 Years of Age
Study ID: NCT05831111
Brief Summary: The purpose of this study is to evaluate the safety and reactogenicity of mRNA-1195 in healthy adults (18 to 55 years of age).
Detailed Description: There will be 2 sequential parts to the study: * Participants will be enrolled in Part A of the study first, which will only enroll those participants who are EBV-seropositive at Screening. * Part B will enroll only those participants who are EBV-seronegative at Screening.
Minimum Age: 18 Years
Eligible Ages: ADULT
Sex: ALL
Healthy Volunteers: Yes
Pinnacle Research Group, LLC, Anniston, Alabama, United States
Noble Clinical Research, Tucson, Arizona, United States
Marvel Clinical Research, Huntington Beach, California, United States
Longmonth Medical Research Network, Longmont, Colorado, United States
Suncoast Research Group, LLC, Miami, Florida, United States
Meridian Clinical Research - Savannah, Savannah, Georgia, United States
Optimal Research, Peoria, Illinois, United States
DM Clinical Research- River Forest, River Forest, Illinois, United States
Meridian Clinical Research, Sioux City, Iowa, United States
Johnson County Clin-Trials, Inc (JCCT), Lenexa, Kansas, United States
Velocity Clinical Research, Rockville, Maryland, United States
DM Clinical Research, Brookline, Massachusetts, United States
University of Mass Medical School, Worcester, Massachusetts, United States
DM Clinical Research, Southfield, Michigan, United States
Meridian Clinical Research, Grand Island, Nebraska, United States
Velocity Clinical Research, Hastings, Nebraska, United States
Meridian Clinical Research, Lincoln, Nebraska, United States
Meridian Clinical Research, Norfolk, Nebraska, United States
Meridian Clinical Research, Omaha, Nebraska, United States
Las Vegas Clinical Trials, LLC, Las Vegas, Nevada, United States
Velocity Clinical Research, Binghamton, New York, United States
Rochester Clinical Research, Inc, Rochester, New York, United States
Tekton Research, Inc, Edmond, Oklahoma, United States
Tekton Research, Inc - Yukon Location, Yukon, Oklahoma, United States
DM Clinical Research - Philadelphia, Philadelphia, Pennsylvania, United States
Alliance for Multispecialty Research, LLC, Knoxville, Tennessee, United States
Benchmark Research, Austin, Texas, United States
Tekton Research Inc., Austin, Texas, United States
CyFair, Houston, Texas, United States
Research Your Health, Plano, Texas, United States
DM Clinical Research, Sugar Land, Texas, United States
DM Clinical Research, Tomball, Texas, United States