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Brief Title: A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 12- to 30-Year-Old Healthy Adolescents and Adults
Official Title: A Phase 1, Randomized, Observer-Blind, Placebo-Controlled, Dose-Ranging Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 12- to 30-Year-Old Healthy Adolescents and Adults
Study ID: NCT05164094
Brief Summary: The main objective of Part A of this trial is to evaluate the safety and reactogenicity of mRNA-1189 in 18- to 30-year-old healthy adults and the main objective of Part B is to evaluate the safety and reactogenicity of mRNA-1189 in 12- to \<18-year-old EBV-seronegative healthy adolescents.
Detailed Description:
Minimum Age: 12 Years
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: Yes
Medical Affiliated Research Institute, Huntsville, Alabama, United States
Care Access Network, Mesa, Arizona, United States
Alliance for Multispecialty Research, LLC, Tempe, Arizona, United States
Smart Cures Clinical Research, Anaheim, California, United States
Velocity Clinical Research - Banning - PPDS, Banning, California, United States
Benchmark Research - Colton - HyperCore - PPDS, Colton, California, United States
Fomat Medical Research, Oxnard, California, United States
Center For Clinical Trials LLC -Paramount, Paramount, California, United States
Artemis Institute For Clinical Research LLC - Riverside - Headlands - PPDS, Riverside, California, United States
Peninsula Research Associates - Headlands Research - PPDS, Rolling Hills, California, United States
Acclaim Clinical Research, San Diego, California, United States
California Research Foundation - 4180 Ruffin Rd, San Diego, California, United States
Orange County Research Center, Tustin, California, United States
Research Centers of America - ERG, Hollywood, Florida, United States
Jacksonville Center For Clinical Research - ERN - PPDS, Jacksonville, Florida, United States
iResearch Savannah - CenExel - PPDS, Savannah, Georgia, United States
Meridian Clinical Research-(Savannah Georgia) - Platinum - PPDS, Savannah, Georgia, United States
Clinical Research Atlanta - Headlands - PPDS, Stockbridge, Georgia, United States
Velocity Clinical Research, Meridian, Idaho, United States
Olivo Medical and Wellness Center, Chicago, Illinois, United States
DM Clinical Research, River Forest, Illinois, United States
Velocity Clinical Research, Valparaiso, Indiana, United States
Meridian Clinical Research, LLC, Sioux City, Iowa, United States
Alliance for Multispecialty Research, LLC - El Dorado - PPDS, El Dorado, Kansas, United States
Johnson County Clin-Trials, Lenexa, Kansas, United States
Alliance for Multispecialty Research LLC, East Wichita, Wichita, Kansas, United States
Michael W Simon MD, PSC, Lexington, Kentucky, United States
Velocity Clinical Research - Lafayette - PPDS, Lafayette, Louisiana, United States
UMass Memorial Medical Center, Worcester, Massachusetts, United States
DM Clinical Research, Southfield, Michigan, United States
Clinical Research Institute, Inc., Minneapolis, Minnesota, United States
Sundance Clinical Research - ERN - PPDS, Saint Louis, Missouri, United States
Meridian Clinical Research (Grand Island, Nebraska), Grand Island, Nebraska, United States
Meridian Clinical Research (Norfolk-Nebraska) - Platinum - PPDS, Norfolk, Nebraska, United States
Quality Clinical Research - ClinEdge - PPDS, Omaha, Nebraska, United States
Meridian Clinical Research-(Omaha Nebraska) - Platinum - PPDS, Omaha, Nebraska, United States
Meridian Clinical Research, LLC (Lincoln Nebraska), Omaha, Nebraska, United States
Alliance for Multispecialty Research, LLC, Las Vegas, Nevada, United States
Meridian Clinical Research, Binghamton, New York, United States
Velocity Clinical Research, East Syracuse, New York, United States
Meridian Clinical Research, Endwell, New York, United States
Lucas Research, Morehead City, North Carolina, United States
Lucas Research, New Bern, North Carolina, United States
Meridian Clinical Research, Cincinnati, Ohio, United States
Lynn Health Science Institute, Oklahoma City, Oklahoma, United States
Velocity Clinical Research, Anderson, South Carolina, United States
Coastal Pediatric Associates, Charleston, South Carolina, United States
Coastal Carolina Research Center, North Charleston, South Carolina, United States
Benchmark Research - Austin - PPDS, Austin, Texas, United States
Tekton Research - Texas - Platinum - PPDS, Austin, Texas, United States
ACRC Trials - Hunt - PPDS, Carrollton, Texas, United States
Velocity Clinical Research - Austin - PPDS, Cedar Park, Texas, United States
Cedar Health Research - Fort Worth - PPDS, Dallas, Texas, United States
Benchmark Research - Fort Worth - HyperCore - PPDS, Fort Worth, Texas, United States
Ventavia Research Group, Houston, Texas, United States
DM Clinical Research - Texas Center For Drug Development - ERN - PPDS, Houston, Texas, United States
DM Clinical Research - Texas Center For Drug Development - ERN - PPDS, Houston, Texas, United States
ACRC Trials - Legacy Medical Village Headquarters, Plano, Texas, United States
ACRC Trials, Plano, Texas, United States
Victoria Clinical Research Group, Victoria, Texas, United States
Tanner Clinic, Layton, Utah, United States
Charlottesville Medical Research Center, Charlottesville, Virginia, United States
Health Research of Hampton Roads Inc. - Newport News, Newport News, Virginia, United States
Alliance for Multispecialty Research, LLC, Norfolk, Virginia, United States
Clinical Research Partners LLC - Richmond - ERN - PPDS, Richmond, Virginia, United States