Spots Global Cancer Trial Database for Influence of Nutrition and Sarcopenia on Esophageal Cancer Outcomes

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Trial Identification

Brief Title: Influence of Nutrition and Sarcopenia on Esophageal Cancer Outcomes

Official Title: Influence of Nutrition and SarcoPenia on Esophageal Cancer ouTcomes (INSPECT Study)

Study ID: NCT06314516

Conditions

Esophageal Cancer

Sarcopenia

Interventions

Study Description

Brief Summary: Prospective multicenter longitudinal (observational) study recruiting from tertiary centers for the surgical management of esophageal cancer; Virginia Mason Medical Center (Seattle, USA) and St Mary's Hospital (Imperial College, London, UK). This is intended to be a pilot study.

Detailed Description: Patients undergoing curative treatment for esophageal cancer will be recruited at the time of routine clinical assessment shortly following initial diagnosis and will undergo clinical and radiological evaluation at two study time points: (1) staging investigation (e.g. laparoscopy or endoscopy) and (2) definitive surgical resection. Study time points have been judiciously chosen to coincide with interventions that form part of patient's routine clinical care. It is intended that sampling will occur on the day of each intervention/surgery following a routine period of fasting.