Spots Global Cancer Trial Database for A Study of Tislelizumab (BGB-A317) Versus Chemotherapy as Second Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma
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Trial Identification
Brief Title: A Study of Tislelizumab (BGB-A317) Versus Chemotherapy as Second Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma
Official Title: A Randomized, Controlled, Open-label, Global Phase 3 Study Comparing the Efficacy of the Anti-PD-1 Antibody Tislelizumab (BGB-A317) Versus Chemotherapy as Second Line Treatment in Patients With Advanced Unresectable/Metastatic Esophageal Squamous Cell Carcinoma
Study ID: NCT03430843
Study Description
Brief Summary: The purpose of this study was to evaluate the efficacy and safety of tislelizumab as second line treatment in participants with advanced unresectable/metastatic ESCC that had progressed during or after first line therapy.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
St. Joseph Heritage Healthcare, Fullerton, California, United States
University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, United States
Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois, United States
Henry Ford Hospital, Detroit, Michigan, United States
Toledo Clinic Cancer Center, Toledo, Ohio, United States
San Antonio Military Medical Center, Fort Sam Houston, Texas, United States
Millennium Oncology, Houston, Texas, United States
Imelda Ziekenhuis, Antwerp, , Belgium
UZ Antwerpen, Antwerp, , Belgium
Cliniques universitaires Saint-Luc, Brussels, , Belgium
University Hospitals Leuven, Leuven, , Belgium
Centre Hospitalier Universitaire (CHU) de Liege - Site du Sart Tilman, Liege, , Belgium
Anhui Medical University - The Second Hospital, Hefei, Anhui, China
Beijing Friendship Hospital, Beijing, Beijing, China
Beijing Cancer Hospital, Beijing, Beijing, China
Peking Union Medical College Hospital, Beijing, Beijing, China
Fujian Medical University Union Hospital, Fuzhou, Fujian, China
The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
Fujian Provincial Cancer Hospital, Fuzhou, Fujian, China
The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China
The First Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China
The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China
Peking University Shenzhen Hospital, Shenzhen, Guangdong, China
Affiliated Hospital of Hebei University, Baoding, Hebei, China
Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China
Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China
The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan, China
Henan Cancer Hospital, Zhengzhou, Henan, China
The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
Hubei Cancer Hospital, Wuhan, Hubei, China
Xiangyang Central Hospital, Xiangyang, Hubei, China
Hunan Cancer Hospital, Changsha, Hunan, China
The First People's Hospital Of Changzhou, Changzhou, Jiangsu, China
Huai'an Second People's Hospital, Huai'an, Jiangsu, China
Jiangsu Province Hospital, Nanjing, Jiangsu, China
Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China
Nantong Tumor Hospital, Nantong, Jiangsu, China
The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China
Jiangxi Cancer Hospital, Nanchang, Jiangxi, China
The First Hospital of Jinlin University, Changchun, Jilin, China
Shandong Cancer Hospital, Jinan, Shandong, China
Shandong Linyi Tumor Hospital, Linyi, Shandong, China
WeiFang People's Hospital, Weifang, Shandong, China
Fudan Cancer Hospital, Shanghai, Shanghai, China
Shanxi Provincial People's Hospital, Taiyuan, Shanxi, China
The Second Affiliated Hospital of Xi'an Jiaotong University(Xibei Hospital), Xi'an, Shanxi, China
Sichuan Academy of Medical Sciences& Sichuan Provincial People's Hospital, Chengdu, Sichuan, China
Yunnan Cancer Hospital - Oncology, Kunming, Yunnan, China
Hangzhou First People's Hospital, Hangzhou, Zhejiang, China
The First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, China
Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China
CHRU Besançon, Besançon, , France
CHRU de Brest Hôpital Morvan, Brest, , France
Centre Georges-Francois Leclerc, Dijon, , France
Center Oscar Lambret - Alliance Member, Lille, , France
Hopital Prive Jean Mermoz, Lyon, , France
ICM Val d'Aurelle, Montpellier, , France
Comprehensive Cancer Center-Gustave Roussy, Paris, , France
Hôpital Haut-Lévêque, Pessac, , France
CHU de Poitiers, Poitiers, , France
Centre de Lutte Contre le Cancer, Saint-Herblain, , France
Clinique Sainte-Anne, Strasbourg, , France
Charite - Universitatsmedizin Berlin /Campus Virchow Klinikum (CVK) - Med. Klinik m. S. Hamatologie, Onkologie und Tumorimmunologie (CC14), Berlin, , Germany
Universitatsklinikum Carl Gustav Carus Dresden, Medizinische Klinik und Poliklinik, Dresden, , Germany
Hamatologisch-Onkologische Praxis Eppendorf (HOPE), Hamburg, , Germany
Asklepios Klinik Altona, Hamburg, , Germany
Universitatsklinikum Koln, Innere Medizin I, Koln, , Germany
Universitat Leipzig, UKL AoR, Universitares Krebszentrum Leipzig (UCCL), Leipzig, , Germany
Universitaetsmedizin der Johannes Gutenberg-Universitat Mainz, Mainz, , Germany
Universitaetsmedizin Mannheim, II. Medizinische Klinik, Mannheim, , Germany
Kliniken Nordoberpfalz, Klinikum Weiden, Weiden, , Germany
PO Garibaldi-Nesima, ARNAS Garibaldi, Catania, , Italy
AUSL della Romagna, Osp. degli Infermi, Faenza, , Italy
Irccs Irst, Meldola, , Italy
AOU - Seconda Università degli Studi di Napoli, Naples, , Italy
AOU San Luigi di Orbassano, Orbassano, , Italy
Ospedale Guglielmo da Saliceto, AUSL Piacenza, Piacenza, , Italy
A.O.U. Pisana, Stabilimento di Santa Chiara, Pisa, , Italy
AO Citta della Salute e della Scienza di Torino - Presidio O, Torino, , Italy
National Cancer Center Hospital East, Kashiwa, Chiba, Japan
Shikoku Cancer Center, Matsuyama, Ehime, Japan
Hyogo Cancer Center, Akashi, Hyogo, Japan
Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan
St. Marianna University School of Medicine Hospital, Kawasaki, Kanagawa, Japan
Kindai University Nara Hospital, Ikoma, Nara, Japan
Osaka University Hospital, Suita, Osaka, Japan
Saitama Cancer Center, Ina, Saitama, Japan
Shizuoka Cancer Center, Nagaizumi, Shizuoka, Japan
National Cancer Center Hospital, Chuo-ku, Tokyo, Japan
The Cancer Institute Hospital of JFCR, Koto-Ku, Tokyo, Japan
Akita University Hospital, Akita, , Japan
Chiba Cancer Center, Chiba, , Japan
National Kyushu Cancer Center, Fukuoka, , Japan
Hiroshima University Hospital, Hiroshima, , Japan
Kagawa University Hospital, Kagawa, , Japan
Kochi Health Sciences Center, Kochi, , Japan
Kyoto University Hospital, Kyoto, , Japan
Osaka International Cancer Institute, Osaka, , Japan
Osaka Medical College Hospital, Osaka, , Japan
Gachon University Gil Medical Center, Incheon, , Korea, Republic of
Seoul National University Bundang Hospital, Seongnam-si, , Korea, Republic of
Asan Medical Center - Oncology, Seoul, , Korea, Republic of
Chonnam National University Hwasun Hospital, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
Korea University Guro Hospital, Seoul, , Korea, Republic of
Hospital del Mar, Barcelona, Madrid, Spain
Hospital Universitario Vall d'Hebron, Barcelona, , Spain
Hospital Clinic de Barcelona, Barcelona, , Spain
Institut Català d'Oncologia, Madrid, , Spain
Hospital Madrid Norte Sanchinarro, Madrid, , Spain
Hospital Universitario Gregorio Marañon, Madrid, , Spain
Hospital Universitario Ramón y Cajal, Madrid, , Spain
Hospital Universitario 12 de Octubre, Madrid, , Spain
Hospital Universitario Virgen de la Arrixaca, Murcia, , Spain
Hospital Universitario Miguel Servet, Zaragoza, , Spain
Changhua Christian Hospital, Changhua, NAP, Taiwan
Chang Gung Medical Foundation - Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, , Taiwan
China Medical University Hospital, Taichung, , Taiwan
Chi Mei Medical Center, Tainan, , Taiwan
Chi Mei Hospital, Liouying, Tainan, , Taiwan
National Taiwan University Hospital, Taipei, , Taiwan
Taipei Veterans General Hospital, Taipei, , Taiwan
Guys & St. Thomas Hospital, London, , United Kingdom
St. George's Hospital, London, , United Kingdom
The Royal Marsden NHS Foundation Trust, London, , United Kingdom
Imperial NHS Trust, London, , United Kingdom
Sarah Cannon Research Institute-London, London, , United Kingdom
The Christie NHS Foundation Trust, Manchester, , United Kingdom
Mount Vernon Cancer Centre, Northwood, , United Kingdom
The Royal Marsden NHS Foundation Trust - Haemato-Oncology, Sutton, , United Kingdom
New Cross Hospital, Wolverhampton, , United Kingdom
Contact Details
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