Spots Global Cancer Trial Database for The Efficacy of N-acetylcysteine on Alleviating Symptom Caused by Lugol Chromoendoscopy
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Trial Identification
Brief Title: The Efficacy of N-acetylcysteine on Alleviating Symptom Caused by Lugol Chromoendoscopy
Official Title: The Efficacy of N-acetylcysteine on Alleviating Symptom Caused by Lugol Chromoendoscopy: a Prospective, Non-inferiority, Randomized Controlled Trial
Study ID: NCT04764643
Conditions
Study Description
Brief Summary: Lugol chromoendoscopy is essential in detecting and characterizing squamous cell carcinoma of esophagus. Esophageal irritating symptom has been reported as an common adverse event, which could be alleviated by sodium thiosulfate solutions. However, sodium thiosulfate was not widely available. N-acetylcysteine has been previously used as a mucolytic reagent, we propose that it may also be used to alleviate irritating symptoms caused by Lugo's chromoendoscopy. A prospective, non-inferior, randomized double-blind clinical trial was designed to study the efficacy of N-acetylcysteine solutions in relieving esophageal discomfort .
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Locations
Xijing Hospital of Digestive Disease, Xi'an, Shaanxi, China
Contact Details
Name: Shaohua Zhu
Affiliation: Xijing Hospital of Digestive DIsease
Role: PRINCIPAL_INVESTIGATOR
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