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Spots Global Cancer Trial Database for Subcutaneous Amifostine (Ethyol®) in the Prevention of Radiochemotherapy-Induced Esophagitis and Pneumonitis in Patients With Unresectable Non-Small Cell Lung Cancer

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Trial Identification

Brief Title: Subcutaneous Amifostine (Ethyol®) in the Prevention of Radiochemotherapy-Induced Esophagitis and Pneumonitis in Patients With Unresectable Non-Small Cell Lung Cancer

Official Title: Phase II, Randomized, Double-Blind, Multicenter Trial of Subcutaneous Amifostine (Ethyol®) Versus Placebo in the Prevention of Radiochemotherapy-Induced Esophagitis and Pneumonitis in Patients With Unresectable Non-Small Cell Lung Cancer

Study ID: NCT00081315

Interventions

Amifostine

Study Description

Brief Summary: The primary objective of this study is to assess the activity of subcutaneous (SC) amifostine on the incidence and severity of acute radiochemotherapy-induced esophagitis in patients with unresectable Stage IIIA or IIIB non-small cell lung cancer (NSCLC) receiving combined modality therapy.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Cedars Sanai, Los Angeles, California, United States

Radiation Oncology Center, Sacramento, California, United States

The Center for Cancer Care, Torrington, Connecticut, United States

Florida Wellcare Alliance, Inverness, Florida, United States

Florida Community Cancer Center, New Port Richey, Florida, United States

Ormand Memorial Cancer Center, Ormand Beach, Florida, United States

Sarasota Memorial Hospital, Sarasota, Florida, United States

University Community Hospital-Center for Cancer Care, Tampa, Florida, United States

University of Kentucky, Lexington, Kentucky, United States

St. Agnes Health Care, Baltimore, Maryland, United States

Center for Cancer & Blood Disorders, Bethesda, Maryland, United States

Chesapeake Oncology-Hematology Associates, Glen Burnie, Maryland, United States

St. John's Medical Research, Springfield, Missouri, United States

Cooper University Hospital, Camden, New Jersey, United States

Long Island Jewish Medical Center, New Hyde Park, New York, United States

Beth Israel Hospital, New York, New York, United States

Upstate NY Cancer R&E Foundation, Rochester, New York, United States

New Hanover Radiation, Wilmington, North Carolina, United States

Cancer Center of Upper Delaware Valley, Milford, Pennsylvania, United States

Montgomery Cancer Center, Norristown, Pennsylvania, United States

Charleston Cancer Center, Charleston, South Carolina, United States

The Center for Radiation Oncology, Danville, Virginia, United States

Providence Everett Medical Center, Everett, Washington, United States

Valley Medical Center, Renton, Washington, United States

Contact Details

Name: Luz Hammershaimb, M.D.

Affiliation: MedImmune LLC

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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