Spots Global Cancer Trial Database for IMRT Tomotherapy for Esophagus Cancer
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Trial Identification
Brief Title: IMRT Tomotherapy for Esophagus Cancer
Official Title: IMRT Tomotherapy for Esophagus Cancer: A Phase I Feasibility Study in Non-Operative Patients
Study ID: NCT00593723
Conditions
Interventions
Study Description
Brief Summary: Concurrent chemotherapy and radiation therapy are the standard of care for inoperable patients with esophagus cancer. Unfortunately, the 5-year survival of 20% for this population is quite low. Methods to intensify radiation therapy delivery without increasing local toxicities are needed. Intensity modulated radiation therapy (IMRT) is an advanced method of delivering external beam radiation that may minimize the volume of normal tissue irradiated to high dose and thus decrease the risk of normal tissue toxicity. The proposed study will prospectively test whether IMRT is tolerable for delivering IMRT doses of 60 Gy for patients with esophagus cancer.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Washington University School of Medicine, St. Louis, Missouri, United States
Contact Details
Name: Jeffrey Bradley, MD
Affiliation: Washington University School of Medicine
Role: PRINCIPAL_INVESTIGATOR
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