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Brief Title: Hydroxychloroquine in Metastatic Estrogen Receptor-Positive Breast Cancer Progressing on Hormonal Therapy
Official Title: Phase Ib/II Study of Hydroxychloroquine in Metastatic ER-Positive Breast Cancer Progressing on Hormonal Therapy
Study ID: NCT02414776
Brief Summary: To determine the safety and tolerability of orally administered hydroxychloroquine with hormonal therapy. To assess the response rate of hydroxychloroquine in combination with hormonal therapy.
Detailed Description: To determine the number of patients with adverse effects To assess the clinical response to the combination
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Western Regional Medical Center, Inc., Goodyear, Arizona, United States
Name: Jiaxin Niu, MD, PhD
Affiliation: Western Regional Medical Center, Inc.
Role: PRINCIPAL_INVESTIGATOR