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Brief Title: High Dose Omeprazole in Patients With Pancreatic Cancer
Official Title: A Phase 0 Study of High Dose Omeprazole in Patients With Pancreatic Cancer Planning to Undergo Surgical Therapy for Evaluating Changes of Biomarkers
Study ID: NCT04930991
Brief Summary: The purpose of this study is to test the safety of high dose omeprazole and see what effects that it has on patients with exocrine pancreatic cancer.
Detailed Description: During this study patients will receive treatment of omeprazole at the dose depending on group enrollment * Group A will receive omeprazole 80 mg, twice a day for 14 days unless unacceptable toxicity * Group B, will receive omeprazole 20 mg, once a day for 14 days Patients will receive treatment for 2\~3 weeks during the study, and 2 months of follow up. Total accrual is anticipated to take 2 years.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Stephenson Cancer Center, Oklahoma City, Oklahoma, United States
Name: Ajay Jain, MD
Affiliation: University of Oklahoma
Role: PRINCIPAL_INVESTIGATOR