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Brief Title: A Study of TQB2450 or Placebo Combined With Anlotinib, Etoposide and Carboplatin Versus Etoposide and Carboplatin in Subjects With Extensive Small Cell Lung Cancer (ETER701)
Official Title: A Randomized, Double-blind, Controlled, Multicenter Phase III Study of TQB2450 or Placebo Combined With Anlotinib, Etoposide and Carboplatin Versus Etoposide and Carboplatin in Subjects With Extensive Small Cell Lung Cancer
Study ID: NCT04234607
Brief Summary: A randomized, double-blind, controlled, multicenter phase III study of TQB2450 or placebo combined with Anlotinib, etoposide and carboplatin versus Etoposide and Carboplatin in subjects with extensive small cell lung cancer. The primary outcome measures include PFS and OS. Extended stage Small Cell Lung Cancer (SCLC) patients will be registered, after signing the informed consent, and then centrally randomized 1:1:1 to the experimental arms and the control arm.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China
Anhui chest hospital, Hefei, Anhui, China
AnHui Provincial Hospital, Hefei, Anhui, China
The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
Beijing chest hospital,capital medical university, Beijing, Beijing, China
Fujian Medical University Union Hospital, Fuzhou, Fujian, China
Fujian Provincial Cancer Hospital, Fuzhou, Fujian, China
Lanzhou University Second Hospital, Lanzhou, Gansu, China
Gansu Provincial Cancer Hospital, Lanzhou, Gansu, China
The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
The Fiest Affiliated Hospital of Guanghzou University of Chinese Medicine, Guangzhou, Guangdong, China
Peking University Shenzhen Hospital, Shenzhen, Guangdong, China
Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China
Guangxi Medical University Affiliated Tumor Hospital, Nanning, Guangxi, China
Guizhou Provincial people's Hospital, Guiyang, Guizhou, China
The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China
Shijiazhuang First Hospital, Shijiazhuang, Hebei, China
Hebei Chest Hospital, Shijiazhuang, Hebei, China
Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China
Henan Cancer Hospital, Zhengzhou, Henan, China
Jinzhou Central Hospital, Jinzhou, Hubei, China
Hunan Cancer Hospital, Changsha, Hunan, China
The First People's Hospital of Lianyungang, Lianyungang, Jiangsu, China
Jilin Cancer Hospital, Changchun, Jilin, China
The Second Hospital of Dalian Medical University, Dalian, Liaoning, China