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Brief Title: Study of Low-Dose Radiotherapy Concurrent Cisplatin/Carboplatin Plus Etoposide With Serplulimab for Patients With ES-SCLC
Official Title: Phase II, Single-Arm Study of Low-Dose Radiotherapy (LDRT) Concurrent Cisplatin/Carboplatin Plus Etoposide With Serplulimab for Patients With Extensive-Stage Small Cell Lung Cancer
Study ID: NCT05765825
Brief Summary: This is a Phase II, single arm, multicenter study designed to evaluate the safety and efficacy of low-dose radiotherapy (LDRT) concurrent cisplatin/carboplatin plus etoposide with serplulimab in participants who have extensive-stage small cell lung cancer (ES-SCLC) and are chemotherapy-navïe for their extensive-stage disease.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China
The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou, GuangGong, China
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
LiaoNing Cancer Hospital & Institute, Shenyang, Liaoning, China
Shandong Provincial Hospital, Jinan, Shandong, China
Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China
China West Hospital, Chengdu, Sichuan, China
Name: You Lu, MD
Affiliation: West China Hospital
Role: STUDY_CHAIR