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Spots Global Cancer Trial Database for Phase II Study of Irinotecan and Cisplatin in Extensive-stage Small Cell Lung Cancer

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Phase II Study of Irinotecan and Cisplatin in Extensive-stage Small Cell Lung Cancer

Official Title: Cisplatin Combined With Irinotecan or Etoposide for Untreated Extensive-stage Small Cell Lung Cancer: a Multicenter Randomized Control Clinical Trial

Study ID: NCT02323737

Study Description

Brief Summary: Patients with untreated extensive-stage small cell lung cancer(SCLC) were randomly assigned to receive either irinotecan/cisplatin (IP) or etoposide/cisplatin(EP), The association of efficacy and toxicity of IP regimen was analyzed.

Detailed Description: This is a randomized, multicenter study. Patients are randomized to irinotecan/cisplatin (IP) or etoposide/cisplatin (EP) treatment arms. The IP regimen consisted of at most 6 cycles of irinotecan 65 mg/m2 of body-surface area on days 1, 8 and cisplatin 75mg/m2 of body-surface area on day 1. The EP regimen consisted of at most 6 cycles of etoposide 100 mg/m2 of body-surface area from day 1 to 3 and cisplatin 75mg/m2 of body-surface area on day 1. Cycle length for the two arms was 3 weeks. The dose adjustment was allowed in at most within ±5% per investigator discretion if necessary.

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Cancer Institute/Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, Beijing, China

Contact Details

Name: yuankai shi, PhD

Affiliation: Cancer Institute/Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College

Role: PRINCIPAL_INVESTIGATOR

Name: xingsheng Hu

Affiliation: Cancer Institute/Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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