Spots Global Cancer Trial Database for TRINOVA-1: A Study of AMG 386 or Placebo, in Combination With Weekly Paclitaxel Chemotherapy, as Treatment for Ovarian Cancer, Primary Peritoneal Cancer and Fallopian Tube Cancer
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Trial Identification
Brief Title: TRINOVA-1: A Study of AMG 386 or Placebo, in Combination With Weekly Paclitaxel Chemotherapy, as Treatment for Ovarian Cancer, Primary Peritoneal Cancer and Fallopian Tube Cancer
Official Title: A Phase 3, Randomized, Double-Blind Trial of Weekly Paclitaxel Plus AMG 386 or Placebo in Women With Recurrent Partially Platinum Sensitive or Resistant Epithelial Ovarian, Primary Peritoneal or Fallopian Tube Cancers
Study ID: NCT01204749
Study Description
Brief Summary: The purpose of this study is to determine if treatment with paclitaxel plus AMG 386 is superior to paclitaxel plus placebo in women with recurrent partially platinum sensitive or resistant epithelial ovarian cancer, primary peritoneal cancer or fallopian tube cancer. AMG 386 is a man-made medication that is designed to stop the development of blood vessels in cancer tissues. Cancer tissues rely on the development of new blood vessels, a process called angiogenesis, to obtain a supply of oxygen and nutrients to grow.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Research Site, Phoenix, Arizona, United States
Research Site, Los Angeles, California, United States
Research Site, San Diego, California, United States
Research Site, Stanford, California, United States
Research Site, Englewood, Colorado, United States
Research Site, Danbury, Connecticut, United States
Research Site, New Haven, Connecticut, United States
Research Site, Hollywood, Florida, United States
Research Site, Orlando, Florida, United States
Research Site, Honolulu, Hawaii, United States
Research Site, Honolulu, Hawaii, United States
Research Site, Boise, Idaho, United States
Research Site, Peoria, Illinois, United States
Research Site, Skokie, Illinois, United States
Research Site, Metairie, Louisiana, United States
Research Site, Baltimore, Maryland, United States
Research Site, Baltimore, Maryland, United States
Research Site, Boston, Massachusetts, United States
Research Site, Boston, Massachusetts, United States
Research Site, Lebanon, New Hampshire, United States
Research Site, Hackensack, New Jersey, United States
Research Site, Brightwaters, New York, United States
Research Site, New York, New York, United States
Research Site, New York, New York, United States
Research Site, Charlotte, North Carolina, United States
Research Site, Charlotte, North Carolina, United States
Research Site, Winston Salem, North Carolina, United States
Research Site, Abington, Pennsylvania, United States
Research Site, Chattanooga, Tennessee, United States
Research Site, Houston, Texas, United States
Research Site, San Antonio, Texas, United States
Research Site, Ogden, Utah, United States
Research Site, Tacoma, Washington, United States
Research Site, Milwaukee, Wisconsin, United States
Research Site, Milwaukee, Wisconsin, United States
Research Site, New Lambton Heights, New South Wales, Australia
Research Site, Greenslopes, Queensland, Australia
Research Site, Bendigo, Victoria, Australia
Research Site, Bentleigh East, Victoria, Australia
Research Site, Footscray, Victoria, Australia
Research Site, Malvern, Victoria, Australia
Research Site, Parkville, Victoria, Australia
Research Site, Edegem, , Belgium
Research Site, Leuven, , Belgium
Research Site, Namur, , Belgium
Research Site, Porto Alegre, Rio Grande do Sul, Brazil
Research Site, Porto Alegre, Rio Grande do Sul, Brazil
Research Site, ItajaÃ-, Santa Catarina, Brazil
Research Site, Ribeirao Preto, São Paulo, Brazil
Research Site, Rio de Janeiro, , Brazil
Research Site, São Paulo, , Brazil
Research Site, Gabrovo, , Bulgaria
Research Site, Plovdiv, , Bulgaria
Research Site, Sofia, , Bulgaria
Research Site, Stara Zagora, , Bulgaria
Research Site, Varna, , Bulgaria
Research Site, Calgary, Alberta, Canada
Research Site, Vancouver, British Columbia, Canada
Research Site, London, Ontario, Canada
Research Site, Toronto, Ontario, Canada
Research Site, Toronto, Ontario, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Sherbrooke, Quebec, Canada
Research Site, Quebec, , Canada
Research Site, Temuco, CautÃ-n, Chile
Research Site, Valparaiso, ValparaÃ-so, Chile
Research Site, Zagreb, , Croatia
Research Site, Brno, , Czech Republic
Research Site, Brno, , Czech Republic
Research Site, Praha 2, , Czech Republic
Research Site, Praha 5, , Czech Republic
Research Site, Tallinn, , Estonia
Research Site, Tartu, , Estonia
Research Site, Amiens, , France
Research Site, Angers, , France
Research Site, Avignon Cedex 2, , France
Research Site, Bayonne, , France
Research Site, Besancon Cedex, , France
Research Site, Bordeaux Cedex, , France
Research Site, Bordeaux Cedex, , France
Research Site, Brest Cedex 2, , France
Research Site, Dijon, , France
Research Site, Le Mans, , France
Research Site, Lille Cedex, , France
Research Site, Lyon, , France
Research Site, Marseille cedex 05, , France
Research Site, Marseille Cedex 09, , France
Research Site, Marseille, , France
Research Site, Montpellier Cedex 5, , France
Research Site, Nancy, , France
Research Site, Nantes Cedex 2, , France
Research Site, Nice cedex 2, , France
Research Site, Orléans cedex 2, , France
Research Site, Paris cedex 15, , France
Research Site, Périgueux cedex, , France
Research Site, Reims Cedex, , France
Research Site, Saint Grégoire cedex, , France
Research Site, Saint Herblain, , France
Research Site, Strasbourg, , France
Research Site, Villejuif cedex, , France
Research Site, Athens, , Greece
Research Site, Heraklion, , Greece
Research Site, Larissa, , Greece
Research Site, Patra, , Greece
Research Site, Thessaloniki, , Greece
Research Site, Hong Kong, , Hong Kong
Research Site, Hyderabad, Andhra Pradesh, India
Research Site, Mumbai, Maharashtra, India
Research Site, Nashik, Maharashtra, India
Research Site, Pune, Maharashtra, India
Research Site, Pune, Maharashtra, India
Research Site, Haifa, , Israel
Research Site, Holon, , Israel
Research Site, Kefar Sava, , Israel
Research Site, Tel Hashomer, , Israel
Research Site, Tel-Aviv, , Israel
Research Site, Benevento, , Italy
Research Site, Catania, , Italy
Research Site, Cosenza (CS), , Italy
Research Site, Genova, , Italy
Research Site, Milano, , Italy
Research Site, Milano, , Italy
Research Site, Napoli, , Italy
Research Site, Padova, , Italy
Research Site, Potenza, , Italy
Research Site, Roma, , Italy
Research Site, Roma, , Italy
Research Site, Nagoya-city, Aichi, Japan
Research Site, Fukuoka-shi, Fukuoka, Japan
Research Site, Kure-city, Hiroshima, Japan
Research Site, Sapporo-city, Hokkaido, Japan
Research Site, Tsukuba-city, Ibaraki, Japan
Research Site, Morioka-city, Iwate, Japan
Research Site, Niigata-city, Niigata, Japan
Research Site, Osakasayama-city, Osaka, Japan
Research Site, Hidaka-Shi, Saitama, Japan
Research Site, Suntou-gun, Shizuoka, Japan
Research Site, Chuo-ku, Tokyo, Japan
Research Site, Yonago-city, Tottori, Japan
Research Site, Kurume-city, , Japan
Research Site, Tokyo, , Japan
Research Site, Tokyo, , Japan
Research Site, Tokyo, , Japan
Research Site, Goyang-si, Gyeonggi-do, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Daugavpils, , Latvia
Research Site, Riga, , Latvia
Research Site, Riga, , Latvia
Research Site, Johor Bahru, Johor, Malaysia
Research Site, Kota Bahru, Kelantan, Malaysia
Research Site, Kuala Lumpur, Wilayah Persekutuan, Malaysia
Research Site, Mexico City, Distrito Federal, Mexico
Research Site, Mexico City, Distrito Federal, Mexico
Research Site, San Luis Potosi, San Luis PotosÃ-, Mexico
Research Site, Distrito Federal, , Mexico
Research Site, Lima, , Peru
Research Site, Lima, , Peru
Research Site, Bydgoszcz, , Poland
Research Site, Gdansk, , Poland
Research Site, Lodz, , Poland
Research Site, Lublin, , Poland
Research Site, Poznan, , Poland
Research Site, Warszawa, , Poland
Research Site, Coimbra, , Portugal
Research Site, Guimaraes, , Portugal
Research Site, Lisboa, , Portugal
Research Site, Porto, , Portugal
Research Site, Porto, , Portugal
Research Site, Santa Maria da Feira, , Portugal
Research Site, Bucharest, , Romania
Research Site, Bucharest, , Romania
Research Site, Cluj Napoca, , Romania
Research Site, Suceava, , Romania
Research Site, Targu Mures, , Romania
Research Site, Ivanovo, , Russian Federation
Research Site, Krasnodar, , Russian Federation
Research Site, Moscow, , Russian Federation
Research Site, Obninsk, , Russian Federation
Research Site, Pyatigorsk, , Russian Federation
Research Site, Saint Petersburg, , Russian Federation
Research Site, Ufa, , Russian Federation
Research Site, Voronezh, , Russian Federation
Research Site, Ljubljana, , Slovenia
Research Site, Groenkloof, Gauteng, South Africa
Research Site, Johannesburg, Gauteng, South Africa
Research Site, Kraaifontein, Western Cape, South Africa
Research Site, Observatory, , South Africa
Research Site, Port Elizabeth, , South Africa
Research Site, Pretoria, , South Africa
Research Site, Córdoba, AndalucÃ-a, Spain
Research Site, Huelva, AndalucÃ-a, Spain
Research Site, Málaga, AndalucÃ-a, Spain
Research Site, Sevilla, AndalucÃ-a, Spain
Research Site, Palma de Mallorca, Baleares, Spain
Research Site, Salamanca, Castilla León, Spain
Research Site, Badalona, Cataluña, Spain
Research Site, Barcelona, Cataluña, Spain
Research Site, Barcelona, Cataluña, Spain
Research Site, Barcelona, Cataluña, Spain
Research Site, Elche, Comunidad Valenciana, Spain
Research Site, Valencia, Comunidad Valenciana, Spain
Research Site, Santiago de Compostela, Galicia, Spain
Research Site, Vigo, Galicia, Spain
Research Site, San Sebastián, PaÃ-s Vasco, Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Umeå, , Sweden
Research Site, Uppsala, , Sweden
Research Site, Baden, , Switzerland
Research Site, Bellinzona, , Switzerland
Research Site, Chur, , Switzerland
Research Site, Geneva 14, , Switzerland
Research Site, Zurich, , Switzerland
Research Site, London, , United Kingdom
Research Site, London, , United Kingdom
Research Site, Manchester, , United Kingdom
Research Site, Northwood, , United Kingdom
Research Site, Nottingham, , United Kingdom
Research Site, Poole, , United Kingdom
Research Site, Sutton, , United Kingdom
Contact Details
Name: MD
Affiliation: Amgen
Role: STUDY_DIRECTOR
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