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Brief Title: Avelumab in First-line NSCLC (JAVELIN Lung 100)
Official Title: A Phase III, Open-label, Multicenter Trial of Avelumab (MSB0010718C) Versus Platinum-based Doublet as a First-line Treatment of Recurrent or Stage IV PD-L1+NSCLC
Study ID: NCT02576574
Brief Summary: The purpose of this study was to demonstrate superiority with regard to Overall Survival (OS) or Progression Free Survival (PFS) of avelumab versus platinum-based doublet, based on an Independent Review Committee assessment, in Non-small cell lung cancer (NSCLC) participants with Programmed death ligand 1+ (PD-L1+) tumors.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Clearview Cancer Institute, Huntsville, Alabama, United States
Arizona Center for Cancer Care, Surprise, Arizona, United States
Sharp Memorial Hospital, San Diego, California, United States
University Cancer Institute, Boynton Beach, Florida, United States
South Georgia Medical Center, Valdosta, Georgia, United States
Christus Cancer Treatment Center, Shreveport, Louisiana, United States
Henry Ford Hospital, Detroit, Michigan, United States
St. Vincent Frontier Cancer Center, Billings, Montana, United States
Nevada Cancer Research Foundation, Las Vegas, Nevada, United States
San Juan Oncology Associates, Farmington, New Mexico, United States
Novant Health Oncology Specialists, Kernersville, North Carolina, United States
Mercy Research, Oklahoma City, Oklahoma, United States
Kaiser Permanente Northwest, Portland, Oregon, United States
Lancaster Cancer Center, Lancaster, Pennsylvania, United States
Cookeville Regional Medical Center, Cookeville, Tennessee, United States
Thompson Cancer Survival Center, Knoxville, Tennessee, United States
Coastal Bend Cancer Center, Corpus Christi, Texas, United States
Oncology Consultants, P.A., Houston, Texas, United States
University of Vermont Medical Center, Burlington, Vermont, United States
Northwest Medical Specialties, PLLC, Tacoma, Washington, United States
Cheyenne Regional Medical Center, Cheyenne, Wyoming, United States
Albury Wodonga Regional Cancer Centre, Albury, New South Wales, Australia
Coffs Harbour Health Campus, Coffs Harbour, New South Wales, Australia
St George Private Hospital, Kogarah, New South Wales, Australia
Lismore Base Hospital, Lismore, New South Wales, Australia
Orange Health Service, Orange, New South Wales, Australia
Royal North Shore Hospital, St Leonards, New South Wales, Australia
Calvary Mater Newcastle, Waratah, New South Wales, Australia
Gallipoli Medical Research Foundation Ltd, Greenslopes, Queensland, Australia
Gold Coast University Hospital, Southport, Queensland, Australia
The Queen Elizabeth Hospital, Woodville South, South Australia, Australia
Ballarat Base Hospital, Ballarat, Victoria, Australia
Bendigo Hospital, Bendigo, Victoria, Australia
South West Healthcare, Warrnambool, Victoria, Australia
Fiona Stanley Hospital, Murdoch, Western Australia, Australia
ZNA Middelheim, Antwerpen, , Belgium
A.Z. Klina, Brasschaat, , Belgium
CHU Ambroise Paré, Mons, , Belgium
NOB - Núcleo de Oncologia da Bahia, Salvador, Bahia, Brazil
CRIO - Centro Regional Integrado de Oncologia, Fortaleza, Ceará, Brazil
CEBROM - Centro Brasileiro de Radioterapia, Oncologia e Mastologia, Goiânia, Goiás, Brazil
Hospital Erasto Gaertner - Liga Paranaense de Combate ao Câncer, Curitiba, Paraná, Brazil
Hospital de Caridade de Ijuí, Ijuí, Rio Grande Do Sul, Brazil
Hospital Bruno Born, Lajeado, Rio Grande Do Sul, Brazil
Hospital São Vicente de Paulo, Passo Fundo, Rio Grande Do Sul, Brazil
Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande Do Sul, Brazil
IMV-Pesquisa Cardiologica Sociedade Simples - HMD - COR, Porto Alegre, Rio Grande Do Sul, Brazil
Hospital São Lucas da PUCRS, Porto Alegre, Rio Grande Do Sul, Brazil
Hospital Nossa Senhora da Conceição, Porto Alegre, Rio Grande Do Sul, Brazil
CEPON - Centro de Pesquisas Oncológicas de Santa Catarina, Florianópolis, Santa Catarina, Brazil
Clínica de Neoplasias Litoral Ltda., Itajaí, Santa Catarina, Brazil
Hospital de Câncer de Barretos - Fundação Pio XII, Barretos, Sao Paulo, Brazil
Fundação Doutor Amaral Carvalho, Jaú, Sao Paulo, Brazil
CEPHO - Centro de Estudos e Pesquisas em Hematologia e Oncologia, Santo Andre, Sao Paulo, Brazil
Fundação Faculdade Regional de Medicina de São José do Rio Preto, São José do Rio Preto, Sao Paulo, Brazil
ICESP - Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira, São Paulo, Sao Paulo, Brazil
IBCC - Instituto Brasileiro de Controle do Câncer, São Paulo, Sao Paulo, Brazil
INCA - Instituto Nacional de Câncer, Rio de Janeiro, , Brazil
Complex Oncological Center - Ruse, EODD, Ruse, , Bulgaria
MHAT for women's health - Nadezhda, OOD, Sofia, , Bulgaria
UMHAT "Sv. Ivan Rilski", EAD, Sofia, , Bulgaria
Shato, Ead, Sofia, , Bulgaria
The Moncton Hospital, Moncton, New Brunswick, Canada
Mount Sinai Hospital, Toronto, Ontario, Canada
FALP - Fundación Arturo López Pérez, Santiago, , Chile
Clinica Santa Maria, Santiago, , Chile
IRAM - Instituto de Radio Medicina, Santiago, , Chile
Hospital Militar de Santiago, Santiago, , Chile
Hospital Clínico San Borja Arriaran, Santiago, , Chile
Hospital Clínico Universidad de Chile, Santiago, , Chile
Hospital Clinico Viña del Mar, Viña del Mar, , Chile
Centro de Investigaciones Clinicas Viña del Mar, Viña del Mar, , Chile
Beijing Cancer Hospital, Beijing, Beijing, China
Guangdong General Hospital, Guangzhou, Guangdong, China
Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China
Liaoning Cancer Hospital & Institute, Shenyang, Liaoning, China
Linyi Cancer Hospital, Linyi, Shandong, China
Administradora Country S.A., Bogotá, , Colombia
Fundación Oftalmológica de Santander - FOSCAL, Floridablanca, , Colombia
Hospital Pablo Tobón Uribe, Medellín, , Colombia
IPS IMAT- Instituto Medico de Alta Tecnologia - Oncomedica S.A., Monteria, , Colombia
University Clinic for Pulmonary Diseases, Zagreb, , Croatia
University Hospital Centre "Sestre Milosrdnice", Zagreb, , Croatia
Bank of Cyprus Oncology Center, Nicosia, , Cyprus
Krajska nemocnice Liberec, a.s., Liberec, , Czechia
Nemocnice Na Plesi s.r.o., Nova Ves pod Plesi, , Czechia
Fakultni nemocnice Olomouc, Olomouc, , Czechia
Vitkovicka nemocnice a.s, Ostrava - Vitkovice, , Czechia
Thomayerova nemocnice, Praha 4 - Krc, , Czechia
Krajska zdravotni, a.s. - Masarykova nemocnice v Usti nad Labem, o.z., Usti nad Labem, , Czechia
Herning Sygehus, Herning, , Denmark
Roskilde Sygehus, Roskilde, , Denmark
North Estonia Medical Centre Foundation, Tallinn, , Estonia
Centre Antoine Lacassagne, Nice cedex 02, Alpes Maritimes, France
CHU de Strasbourg - Nouvel Hôpital Civil, Strasbourg, Bas Rhin, France
Hôpital Nord - AP-HM Marseille#, Marseille cedex 20, Bouches-du-Rhône, France
Hôpital privé Clairval, Marseille, Bouches-du-Rhône, France
CHU Besançon - Hôpital Jean Minjoz, Besancon Cedex, Doubs, France
CHU Brest - Hôpital Morvan, Brest Cedex, Finistere, France
Groupe Hospitalier Sud - Hôpital Haut-Lévêque, Pessac, Gironde, France
CHU Angers - Hôpital Hôtel Dieu#, Angers Cedex 9, Maine Et Loire, France
Hôpital Cochin, Paris cedex 14, Paris, France
Centre Hospitalier de la Côte Basque, Bayonne, Pyrenees Atlantiques, France
Centre Hospitalier de la Croix Rousse, Lyon cedex 04, Rhone, France
Clinique Victor Hugo - Centre Jean Bernard, Le Mans Cedex 02, Sarthe, France
Institut Sainte Catherine, Avignon Cedex 9, Vaculuse, France
Centre Hospitalier Intercommunal de Créteil, Creteil cedex, Val De Marne, France
Hôpital Saint-Louis - Paris, Paris Cedex 10, , France
Universitaetsklinikum Heidelberg, Heidelberg, Baden Wuerttemberg, Germany
LungenClinic Grosshansdorf GmbH, Grosshansdorf, Schleswig Holstein, Germany
251 General Air Force Hospital, Athens, , Greece
General Hospital of Athens of Chest Diseases "SOTIRIA", Athens, , Greece
University General Hospital "Attikon", Athens, , Greece
General Oncology Hospital of Kifissia " Agioi Anargyroi", Athens, , Greece
Metropolitan General Hospital, Athens, , Greece
University General Hospital of Heraklion, Heraklion, , Greece
University General Hospital of Patra, Patras, , Greece
Euromedica General Clinic Thessaloniki, Thessaloniki, , Greece
Orszagos Koranyi Pulmonologiai Intezet, Budapest, , Hungary
Orszagos Onkologiai Intezet, Budapest, , Hungary
Semmelweis Egyetem, Budapest, , Hungary
Orszagos Koranyi Pulmonologiai Intezet, Budapest, , Hungary
Csongrad Megyei Mellkasi Betegsegek Szakkorhaza, Deszk, , Hungary
Petz Aladar Megyei Oktato Korhaz, Györ, , Hungary
Borsod-Abauj-Zemplen Megyei Kozponti Korhaz es Egyetemi Oktatokorhaz, Miskolc, , Hungary
SzSzB Megyei Korhazak es Egyetemi Oktatokorhaz, Nyiregyhaza, , Hungary
Tolna Megyei Balassa Janos Korhaz, Szekszard, , Hungary
Tudogyogyintezet Torokbalint, Torokbalint, , Hungary
Zala Megyei Szent Rafael Korhaz, Zalaegerszeg, , Hungary
Cork University Hospital, Cork, , Ireland
Soroka University Medical Center, Beer Sheva, , Israel
Rambam Health Care Center, Haifa, , Israel
Hadassah University Hospital - Ein Kerem, Jerusalem, , Israel
Sapir Medical Center, Meir Hospital, Kfar-Saba, , Israel
Rabin Medical Center-Beilinson Campus, Petach Tikva, , Israel
Chaim Sheba Medical Center, Ramat Gan, , Israel
Kaplan Medical Center, Rechovot, , Israel
Assaf Harofeh, Rishon Lezion, , Israel
Tel Aviv Sourasky Medical Center, Tel Aviv, , Israel
Ospedale Mater Salutis, Legnago, Verona, Italy
Fondazione Poliambulanza Istituto Ospedaliero, Brescia, , Italy
Presidio Ospedaliero Garibaldi Nesima, Catania, , Italy
Azienda Ospedaliero Universitaria San Martino, Genova, , Italy
Seconda Università degli Studi di Napoli, Napoli, , Italy
Azienda Ospedaliero Universitaria di Parma, Parma, , Italy
Azienda Ospedaliero Universitaria Pisana, Pisa, , Italy
National Cancer Center Hospital East, Kashiwa-shi, Chiba-Ken, Japan
Kurume University Hospital, Kurume-shi, Fukuoka-Ken, Japan
NHO Hokkaido Cancer Center, Sapporo-shi, Hokkaido, Japan
Institute of Biomedical Research and Innovation Hospital, Kobe-shi, Hyogo-Ken, Japan
Kobe City Hospital Organization Kobe City Medical Center General Hospital, Kobe-shi, Hyogo-Ken, Japan
Yokohama Municipal Citizen's Hospital, Yokohama-shi, Kanagawa-Ken, Japan
Kanagawa Cancer Center, Yokohama-shi, Kanagawa-Ken, Japan
Kansai Medical University Hospital, Hirakata-shi, Osaka-Fu, Japan
Osaka Medical College Hospital, Takatsuki-shi, Osaka-Fu, Japan
National Cancer Center Hospital, Chuo-ku, Tokyo-To, Japan
Tokyo Medical University Hospital, Shinjuku-ku, Tokyo-To, Japan
Toyama University Hospital, Toyama-shi, Toyama-Ken, Japan
Kobe City Hospital Organization Kobe City Medical Center General Hospital, Kobe-shi, , Japan
Chungbuk National University Hospital, Cheongju-si, Chungcheongbuk-do, Korea, Republic of
Yonsei University Wonju Severance Christian Hospital, Wonju-si, Gangwon-do, Korea, Republic of
Inje University Haeundae Paik Hospital, Busan, Gyeonggi-do, Korea, Republic of
National Cancer Center, Goyang-si, Gyeonggi-do, Korea, Republic of
CHA Bundang Medical Center, CHA University, Seongnam-si, Gyeonggi-do, Korea, Republic of
Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea, Republic of
The Catholic University of Korea, St. Vincent's Hospital, Suwon-si, Gyeonggi-do, Korea, Republic of
Ajou University Hospital, Suwon-si, Gyeonggi-do, Korea, Republic of
Kyungpook National University Chilgok Hospital, Daegu, , Korea, Republic of
Gachon University Gil Medical Center, Incheon, , Korea, Republic of
Korea University Anam Hospital, Seoul, , Korea, Republic of
Seoul National University Hospital, Seoul, , Korea, Republic of
Severance Hospital, Yonsei University, Seoul, , Korea, Republic of
Asan Medical Center, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, , Korea, Republic of
The Catholic University of Korea, Yeouido St. Mary's Hospital, Seoul, , Korea, Republic of
Korea University Guro Hospital, Seoul, , Korea, Republic of
Ulsan University Hospital, Ulsan, , Korea, Republic of
American University of Beirut Medical Center, Beirut, , Lebanon
Rafik Hariri University Hospital, Beirut, , Lebanon
Hotel Dieu de France Hospital, Beirut, , Lebanon
Mount Lebanon Hospital, Beirut, , Lebanon
Hammoud Hospital University Medical Center, Saida, , Lebanon
Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Kaunas, , Lithuania
Martini Ziekenhuis, Groningen, , Netherlands
Westfriesgasthuis - PARENT, Hoorn, , Netherlands
ETZ Elisabeth, Tilburg, , Netherlands
Auckland City Hospital, Auckland, , New Zealand
Dunedin Public Hospital, Dunedin, , New Zealand
Waikato Hospital, Hamilton, , New Zealand
Palmerston North Hospital, Palmerston North, , New Zealand
Tauranga Hospital, Tauranga, , New Zealand
Wellington Hospital, Wellington, , New Zealand
Instituto Nacional de Enfermedades Neoplásicas, Lima, , Peru
Clinica Internacional Sede San Borja, Lima, , Peru
Oncosalud, Lima, , Peru
Centrum Terapii Wspolczesnej J.M. Jasnorzewska sp. komandytowo-akcyjna, Lodz, , Poland
Instytut MSF Sp. o.o, Lodz, , Poland
Wojewódzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Łodzi, Lodz, , Poland
KO-MED Centra Kliniczne Lublin II, Lublin, , Poland
SSZZOZ im. Dr Teodora Dunina w Rudce, Mrozy, , Poland
SP Zespol Gruzlicy i Chorob Pluc w Olsztynie, Olsztyn, , Poland
Mazowieckie Centrum Leczenia Chorob Pluc i Gruzlicy, Otwock, , Poland
Szpital Kliniczny Przemienienia Panskiego Uniwersytetu Medycznego im. Karola Marcinkowskiego, Poznan, , Poland
Izerskie Centrum Pulmonologii i Chemioterapii "IZER-MED" Spolka z o.o., Szklarska Poręba, , Poland
Centrum Onkologii-Instytut im. M. Sklodowskiej Curie, Warszawa, , Poland
Mazowiecki Szpital Onkologiczny, Wieliszew, , Poland
Hospital Garcia de Orta, EPE, Almada, , Portugal
Hospital Professor Doutor Fernando Fonseca, E.P.E., Amadora-Lisbon, , Portugal
Centro Hospitalar De Coimbra-CHUC, Coimbra, , Portugal
Centro Hospitalar e Universitário de Coimbra, E.P.E (CHC), Coimbra, , Portugal
Centro Hospitalar de Lisboa Norte, E.P.E. - Hospital Pulido Valente, Lisboa, , Portugal
Centro Hospitalar de Lisboa Central, E.P.E. - Hospital de Santo António dos Capuchos, Lisboa, , Portugal
Centro Hospitalar do Porto, E.P.E. - Hospital de Santo António, Porto, , Portugal
Hospital CUF Porto, Porto, , Portugal
Instituto Português de Oncologia do Porto Francisco Gentil, EPE, Porto, , Portugal
Centro Hospitalar de São João, E.P.E., Porto, , Portugal
Centro Hospitalar de Entre o Douro e Vouga, E.P.E - Hospital de São Sebastião, Santa Maria da Feira, , Portugal
Centro Hospitalar Vila Nova de Gaia/Espinho, E.P.E, Vila Nova de Gaia, , Portugal
Spitalul Judetean de Urgenta "Dr. Constantin Opris" Baia Mare, Baia Mare, , Romania
S.C Policlinica de Diagnostic Rapid S.A, Brasov, , Romania
Institutul Oncologic "Prof. Dr. Al. Trestioreanu", Bucuresti, , Romania
Spitalul Clinic Coltea, Bucuresti, , Romania
S.C Gral Medical S.R.L, Bucuresti, , Romania
Institutul Oncologic "Prof. Dr. Ion Chiricuta" Cluj Napoca, Cluj Napoca, , Romania
S.C Medisprof S.R.L, Cluj-Napoca, , Romania
Spitalul Militar de Urgenta "Dr.Constantin Papilian"Cluj -Napoca, Cluj-Napoca, , Romania
S.C Radiotherapy Center Cluj S.R.L, Comuna Floresti, , Romania
Spitalul Clinic Judetean de Urgenta "Sf. Apostol Andrei" Constanta, Constanta, , Romania
S.C Centrul de Oncologie Sf. Nectarie S.R.L, Craiova, , Romania
Institutul Regional de Oncologie Iasi, Iasi, , Romania
S.C Pelican Impex S.R.L, Oradea, , Romania
Spitalul Clinic Municipal "Dr. Gavril Curteanu" Oradea, Oradea, , Romania
Spitalul Judetean de Urgenta "Sf. Ioan cel Nou" Suceava, Suceava, , Romania
S.C Oncocenter Oncologie Clinica S.R.L, Timisoara, , Romania
S.C Oncomed S.R.L, Timisoara, , Romania
SBIH of Arkhangelsk region "Arkhangelsk Clinical Oncological Dispensary", Arkhangelsk, , Russian Federation
LLC Evimed, Chelyabinsk, , Russian Federation
Chelyabinsk Regional Oncology Dispensary, Chelyabinsk, , Russian Federation
Irkutsk Regional Oncology Dispensary, Irkutsk, , Russian Federation
RBIH "Ivanovo Regional Oncological Dispensary", Ivanovo, , Russian Federation
SBHI of Kaluga Region "Kaluga regional clinical oncology dispensary", Kaluga, , Russian Federation
SAIH "Republican Clinical Oncological Dispensary of the Ministry of Healthcare of Republic Tatarstan, Kazan, , Russian Federation
Kemerovo SPI Regional Clinical Oncology Dispensary, Kemerovo, , Russian Federation
SBHI "Krasnoyarsk Regional Oncology Dispensary n.a. A.I. Kryzhanovsky", Krasnoyarsk, , Russian Federation
RBIH "Kursk regional clinical oncology dispensary" of Kursk Region Healthcare Committee, Kursk, , Russian Federation
FSBSI "Russian Oncological Scientific Center n.a. N.N. Blokhin", Moscow, , Russian Federation
Murmansk Regional Clinical Hospital named after Bayandin, Murmansk, , Russian Federation
SBHI of Novosibirsk region "Novosibirsk Regional Oncological Dispensary", Novosibirsk, , Russian Federation
SBIH of Stavropol territory "Pyatigorsk Oncological Dispensary", Pyatigorsk, , Russian Federation
SBIH "Leningrad Regional Oncological Dispensary", Saint-Petersburg, , Russian Federation
"Bio Eq" LLC, Saint-Petersburg, , Russian Federation
FBI "Scientific Research Institute of Oncology n. a. N. N. Petrov", Saint-Petersburg, , Russian Federation
SBIH "Samara Regional Clinical Oncological Dispensary", Samara, , Russian Federation
SBIH "Oncological Dispensary # 2" of the MoH of Krasnodar territory, Sochi, , Russian Federation
FSBHI Clinical research institute of phthisiopulmonology, St. Petersburg, , Russian Federation
Tomsk Research Instutite of Oncology, Tomsk, , Russian Federation
BHI of Omsk region "Clinical Oncology Dispensary", Tomsk, , Russian Federation
Medicinskiy gorod, Tyumen, , Russian Federation
SBIH of Yaroslavl region "Regional Clinical Oncological Hospital", Yaroslavl, , Russian Federation
Clinical Center of Serbia, Belgrade, , Serbia
Institute of Oncology and Radiology of Serbia, Belgrade, , Serbia
Military Medical Academy, Belgrade, , Serbia
Clinical Center Bezanijska Kosa, Belgrade, , Serbia
Clinical Center Nis, Pulmonary Diseases Clinic, Gornji Matejevac, , Serbia
Clinical Center Kragujevac, Kragujevac, , Serbia
Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, , Serbia
National University Cancer Institute, Singapore, , Singapore
National Cancer Centre, Singapore, , Singapore
Tan Tock Seng Hospital, Singapore, , Singapore
Nemocnica s poliklinikou Sv. Jakuba, n.o. Bardejov, Bardejov, , Slovakia
Univerzitna nemocnica Bratislava, Nemocnica Ruzinov, Bratislava, , Slovakia
Emery Clinical Services, Alberton, Gauteng, South Africa
University of Pretoria Oncology Department, Pretoria, Gauteng, South Africa
Johese Clinical Research, Pretoria, Gauteng, South Africa
Cape Town Oncology Trials Pty Ltd, Cape Town, Western Cape, South Africa
Hospital de Mataro, Mataro, Barcelona, Spain
Hospital Universitario Mutua de Terrassa, Terrassa, Barcelona, Spain
Hospital Universitario Donostia, San Sebastian, Guipuzcoa, Spain
Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, La Coruña, Spain
Complejo Hospitalario Universitario de Vigo, Vigo, Pontevedra, Spain
Specialist, Barcelona, , Spain
Hospital Universitari Quiron Dexeus, Barcelona, , Spain
Hospital Universitari Vall d'Hebron, Barcelona, , Spain
Hospital de la Santa Creu i Sant Pau, Barcelona, , Spain
ICO Girona - Hospital Universitari de Girona Dr. Josep Trueta, Girona, , Spain
Hospital General Universitario Gregorio Marañon, Madrid, , Spain
MD Anderson Cancer Centre, Madrid, , Spain
Fundacion Jimenez Diaz, Madrid, , Spain
Hospital Universitario La Paz, Madrid, , Spain
Hospital Regional Universitario de Malaga, Málaga, , Spain
Hospital Quiron Sagrado Corazon, Sevilla, , Spain
Hospital Universitario Virgen del Rocio, Sevilla, , Spain
Hospital Txagorritxu, Vitoria, , Spain
Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, , Taiwan
China Medical University Hospital, Taichung, , Taiwan
Taichung Veterans General Hospital, Taichung, , Taiwan
National Taiwan University Hospital, Taipei, , Taiwan
Taipei Veterans General Hospital, Taipei, , Taiwan
Tri-Service General Hospital, Taipei, , Taiwan
Chang Gung Memorial Hospital, Linkou, Taoyuan County, , Taiwan
King Chulalongkorn Memorial Hospital, Patumwan, Bangkok, Thailand
Rajavithi Hospital, Rajathevee, Bangkok, Thailand
Maharaj Nakorn Chiang Mai Hospital, Muang, Chiang Mai, Thailand
Srinagarind Hospital, Muang, Khon Kaen, Thailand
Naresuan University Hospital, Muang, Phitsanulok, Thailand
Songklanagarind Hospital, Hat Yai, Songkhla, Thailand
Siriraj Hospital, Bangkok, , Thailand
Acibadem Adana Hospital, Adana, , Turkey
Baskent University Adana Application and Research Center, Adana, , Turkey
Adana Numune Training and Research Hospital, Adana, , Turkey
Cukurova University Medical Faculty, Adana, , Turkey
Adana City Hospital, Adana, , Turkey
Ankara University Medical Faculty, Ankara, , Turkey
Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, , Turkey
Hacettepe University Medical Faculty, Ankara, , Turkey
Memorial Antalya Hastanesi, Antalya, , Turkey
Okmeydani Research and Training Hospital, Istanbul, , Turkey
Istanbul University Cerrahpasa Medical Faculty, Istanbul, , Turkey
Bakirkoy Dr. Sadi Konuk Teaching and Research Hospital, Istanbul, , Turkey
Medipol University Medical Faculty, Istanbul, , Turkey
Kartal Lutfi Kirdar Research and Training Hospital, Istanbul, , Turkey
Ege University Medical Faculty, Izmir, , Turkey
Inonu Uni. Med. Fac., Malatya, , Turkey
Mersin University Medical Faculty, Mersin, , Turkey
Sakarya Traning and Research Hospital, Sakarya, , Turkey
Namik Kemal University, Tekirdag, , Turkey
CI Chernivtsi RC Oncological Dispensary Bukovinian SMU Ch of Oncology and Radiology, Chernivtsi, , Ukraine
CI Dnipropetrovsk CMCH #4 of Dnipropetrovsk RC Dept of Chemotherapy SI Dnipropetrovsk MA of MOHU, Dnipro, , Ukraine
CI Transcarpathian Cl Onc Center Dep of Surgery#1 SHEI Ivano-Frankivsk NMU, Ivano-Frankivsk, , Ukraine
SI S.P.Grygoriev Institute of Medical Radiology of NAMSU, Kharkiv, , Ukraine
Communal Non-profit Enterprise Regional Center of Oncology, Kharkiv, , Ukraine
Kherson Regional Oncologic Dispensary, Kherson, , Ukraine
Treatment-Diagnostic Center of Private Enterprise of PPC Atsynus, Kropyvnytskyi, , Ukraine
CI Kryvyi Rih Oncological Dispensary of DRC, Kryvyi Rih, Dnipropetrovsk Region, , Ukraine
Kyiv City Clinical Oncological Center, Kyiv, , Ukraine
Treatment-Prevention Institution Volyn Regional Oncological Dispensary, Lutsk, , Ukraine
Lviv State Oncological Regional Treatment and Diagnostic Center, Lviv, , Ukraine
Odesa Regional Oncologic Dispensary, Odesa, , Ukraine
RCI Sumy Regional Clinical Oncological Dispensary, Sumy, , Ukraine
CCCH City Oncological Center SHEI Uzhgorod NU, Uzhgorod, , Ukraine
Podilskyi Regional Oncological Center, Vinnytsia, , Ukraine
Vinnytsia Regional Clinical Oncological Dispensary, Vinnytsia, , Ukraine
Southend University Hospital, Westcliff on Sea, Essex, United Kingdom
Cheltenham General Hospital, Cheltenham, Gloucestershire, United Kingdom
Chelsea and Westminster Hospital, London, Greater London, United Kingdom
Mount Vernon Hospital, Stevenage, Hertfordshire, United Kingdom
The Clatterbridge Cancer Centre, Wirral, Merseyside, United Kingdom
Royal Stoke University Hospital, Stoke on Trent, Staffordshire, United Kingdom
Name: Medical Responsible
Affiliation: EMD Serono Inc., an affiliate of Merck KGaA, Darmstadt, Germany
Role: STUDY_DIRECTOR