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Spots Global Cancer Trial Database for Safety & Efficacy Study of AT-101 in Combination w/ Rituximab in Previously Untreated Grade I-II Follicular Non-Hodgkin's Lymphoma

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Trial Identification

Brief Title: Safety & Efficacy Study of AT-101 in Combination w/ Rituximab in Previously Untreated Grade I-II Follicular Non-Hodgkin's Lymphoma

Official Title: An Open-label, Multicenter, Phase II Study of AT-101 in Combination With Rituximab in Patients With Untreated, Grade I-II, Follicular Non-Hodgkin's Lymphoma

Study ID: NCT00440388

Interventions

AT-101
Rituximab

Study Description

Brief Summary: This is a phase II clinical trial in patients who have not received systemic treatment for follicular non-Hodgkin's lymphoma. The study combines rituximab, an approved drug for this disease, with AT-101, an experimental drug. The hypothesis is that by adding AT-101 to the rituximab regimen, improvement to patients' response to the treatment will be observed verses rituximab alone.

Detailed Description: Further Study Details provided by Ascenta.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Alabama at Birmingham, Birmingham, Alabama, United States

Hematology Oncology Associates, Phoenix, Arizona, United States

Rocky Mountain Cancer Center-Aurora, Aurora, Colorado, United States

Florida Cancer Institute, Hudson, Florida, United States

Florida Cancer Institute, New Port Richey, Florida, United States

Cancer Care & Hematology Specialists of Chicagoland, Arlington Heights, Illinois, United States

Central Indiana Cancer Centers, Fishers, Indiana, United States

University of Michigan Cancer Center, Ann Arbor, Michigan, United States

Minnesota Oncology Hematology, P.A., Minneapolis, Minnesota, United States

Missouri Cancer Associates, Columbia, Missouri, United States

Comprehensive Cancer Centers of Nevada, Henderson, Nevada, United States

Hematology/Oncology Associates, Albuquerque, New Mexico, United States

New York Oncology Hematology, P.C., Albany, New York, United States

Duke University Medical Center, Durham, North Carolina, United States

Northwest Cancer Specialists, Portland, Oregon, United States

The Jones Clinic, Germantown, Tennessee, United States

Texas Oncology, P.A., Bedford, Texas, United States

Texas Cancer Center at Medical City, Dallas, Texas, United States

Texas Oncology, P.A., Fort Worth, Texas, United States

Allison Cancer Center, Midland, Texas, United States

HOAST - New Braunfels, New Braunfels, Texas, United States

West Texas Cancer Center, Odessa, Texas, United States

Hematology Oncology Physicians of Texas, Richardson, Texas, United States

Tyler Cancer Center, Tyler, Texas, United States

Virginia Oncology Associates, Chesapeake, Virginia, United States

Oncology and Hematology Associates of SW Virginia, Inc., Salem, Virginia, United States

Cancer Care Northwest, Spokane, Washington, United States

St. Mary's Medical Center, Huntington, West Virginia, United States

Contact Details

Name: Lance Leopold, MD

Affiliation: Ascenta Therapeutics, Inc.

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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