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Brief Title: Phase 3 Study of Zevalin Following R-CVP in Previously Untreated Patients With Follicular Non Hodgkin's Lymphoma (NHL)
Official Title: A Phase 3 Open Label Multicenter, Randomized Study to Compare the Efficacy and Safety of the Zevalin (Ibritumomab Tiuxetan) Therapeutic Regimen Following Cyclophosphamide, Vincristine, Prednisone, and Rituximab (R-CVP) With R-CVP Alone in High-Risk Subjects With Previously Untreated CD20-Positive Follicular Non-Hodgkin's Lymphoma
Study ID: NCT00384111
Brief Summary: This study will treat follicular lymphoma patients who have not received previous treatment with R-CVP. Half of the patients will receive Zevalin after R-CVP and the other half will receive only R-CVP. The two patient groups will be compared to determine if Zevalin given after R-CVP therapy provides greater benefits than receiving no additional anti-cancer therapy after R-CVP.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Integrated Community Oncology Network, Jacksonville, Florida, United States
Gulfcoast Oncology Associates, Saint Petersburg, Florida, United States
Wellstar-Northwest Georgia Oncology Centers, Marietta, Georgia, United States
Oncology Hematology Care Inc., Cincinnati, Ohio, United States
Chattanooga Oncology Hematology Care, Chattanooga, Tennessee, United States
Tennessee Oncology, Nashville, Tennessee, United States