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Brief Title: Study of HCD122 (Lucatumumab) and Bendamustine Combination Therapy in CD40+ Rituximab-refractory Follicular Lymphoma
Official Title: A Phase Ib, Multicenter, Open-label Study of HCD122 Administered Intravenously in Combination With Bendamustine in Patients With CD40+ Follicular Lymphoma Who Are Refractory to Rituximab
Study ID: NCT01275209
Brief Summary: This study will assess the safety and efficacy of HCD122 (Lucatumumab) when combined with bendamustine in patients with follicular lymphoma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Dana Farber Cancer Institute SC-5, Boston, Massachusetts, United States
Wayne State University/Karmanos Cancer Institute Dept.of KarmanosCancerInst (6), Detroit, Michigan, United States
Duke University Medical Center Duke Hem & Onc, Durham, North Carolina, United States
Sarah Cannon Research Institute SC - 2, Chattanooga, Tennessee, United States
Novartis Investigative Site, Prahran, Victoria, Australia
Novartis Investigative Site, Gent, , Belgium
Novartis Investigative Site, Leuven, , Belgium
Novartis Investigative Site, Toronto, Ontario, Canada
Novartis Investigative Site, Paris, , France
Novartis Investigative Site, Torino, TO, Italy
Novartis Investigative Site, Barcelona, Cataluña, Spain
Novartis Investigative Site, Madrid, , Spain
Name: Novartis Pharmaceuticals
Affiliation: Novartis Pharmaceuticals
Role: STUDY_DIRECTOR