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Brief Title: Perioperative Treatment of Combined SOX With Apatinib and Camrelizumab for Oesophagogastric Cancer
Official Title: Perioperative Treatment of Combined SOX With Apatinib and Camrelizumab for Resectable Locally Advanced Gastric or Esophagogastric Junction Adenocarcinoma: A Multicenter, Randomized Phase II-III Trial
Study ID: NCT04208347
Brief Summary: The study is being conducted to evaluate the efficacy, safety and tolerability of chemotherapy and apatinib with or without camrelizumab in the neoadjuvant (prior to surgery) or adjuvant (after surgery) treatment of previously untreated adults with gastric and gastroesophageal junction (GEJ) adenocarcinoma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Affiliated Hospital of Hebei University, Baoding, , China
Cancer Hospital Chinese Academy of Medical Sciences, Beijing, , China
Xiangya Hospital Central South University, Changsha, , China
Heping Hospital Affiliated to Changzhi Medical College, Changzhi, , China
Sichuan Cancer Hospital & Institute, Chengdu, , China
Sichuan Provincial People's Hospital, Chengdu, , China
The Affiliated Hospital of Guizhou Medical University, Guiyang, , China
Hainan Cancer Hospital, Haikou, , China
Cancer Hospital of the University of Chinese Academy of Sciences, Hangzhou, , China
The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, , China
Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, , China
Lanzhou University Second Hospital, Lanzhou, , China
Changhai Hospital, Shanghai, , China
Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, , China
Liaoning Cancer Hospita & Institute, Shenyang, , China
The Fourth Hospital of Hebei Medical University, Shijiazhuang, , China
Jilin Guowen Hospital, Siping, , China
Shanxi Provincial Cancer Hospital, Taiyuan, , China
First Affiliated Hospital of Xi'an Jiaotong University, Xian, , China
Tangdu Hospital, Xian, , China
Yantai Yuhuangding Hospital, Yantai, , China
Henan Provincial Cancer Hospital, Zhengzhou, , China
Affiliated Hospital of Jiangsu University, Zhenjiang, , China
Name: Zhenggang Zhu
Affiliation: Ruijin Hospital
Role: PRINCIPAL_INVESTIGATOR