Spots Global Cancer Trial Database for Gastric Cancer Prevention in the Family Members by Helicobacter Pylori Eradication
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Trial Identification
Brief Title: Gastric Cancer Prevention in the Family Members by Helicobacter Pylori Eradication
Official Title: Helicobacter Pylori Eradication to Prevent Gastric Cancer in Subjects With Family History of Gastric Cancer: A Randomized Controlled Study
Study ID: NCT01678027
Study Description
Brief Summary: This study evaluate whether treatment of Helicobacter pylori infection reduces the incidence of gastric cancer in subjects with family history of gastric cancer.
Detailed Description: Helicobacter pylori infection is associated with gastric cancer in epidemiological studies. However, it is still unknown whether H. pylori eradication is useful and required to prevent gastric cancer. Gastric cancer risk is increased in family members of gastric cancer patient. Though there is no direct evidence that H. pylori infection is a risk factor for gastric cancer in family members of gastric cancer, current European guideline recommends H. pylori eradication in first-degree relatives of gastric cancer patients. In this study, the investigators will evaluate whether H. pylori eradication can reduce gastric cancer risk in the first-degree family members of gastric cancer patients.
Eligibility
Minimum Age: 40 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Locations
National Cancer Center, Korea, Goyang, Gyeonggi, Korea, Republic of
Contact Details
Name: Il Ju Choi, M.D., Ph.D.
Affiliation: National Cancer Center, Korea
Role: PRINCIPAL_INVESTIGATOR
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