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Brief Title: Bemarituzumab Plus Chemotherapy and Nivolumab Versus Chemotherapy and Nivolumab for FGFR2b Overexpressed Untreated Advanced Gastric and Gastroesophageal Junction Cancer
Official Title: A Phase 1b/3 Study of Bemarituzumab Plus Chemotherapy and Nivolumab Versus Chemotherapy and Nivolumab Alone in Subjects With Previously Untreated Advanced Gastric and Gastroesophageal Junction Cancer With FGFR2b Overexpression
Study ID: NCT05111626
Brief Summary: The main objective of Part 1 is to evaluate the safety and tolerability of bemarituzumab plus 5-fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) and nivolumab. The main objective Part 2 is to compare efficacy of bemarituzumab plus chemotherapy (mFOLFOX6 or capecitabine combined with oxaliplatin (CAPOX)) and nivolumab to placebo plus chemotherapy (mFOLFOX6 or CAPOX) and nivolumab as assessed by overall survival.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Mayo Clinic - Arizona, Phoenix, Arizona, United States
The Oncology Institute Clinical Research, Cerritos, California, United States
Cancer and Blood Specialty Clinic, Downey, California, United States
City of Hope National Medical Center, Duarte, California, United States
University of California Los Angeles, Los Angeles, California, United States
University of California Irvine, Orange, California, United States
Torrance Memorial Physician Network, Redondo Beach, California, United States
Translational Research in Oncology - US Inc, Santa Monica, California, United States
Translational Research in Oncology US Inc, Trio Central Pharmacy, Santa Monica, California, United States
Olive View-University of California in Los Angeles Medical Center, Sylmar, California, United States
Presbyterian Intercommunity Hospital Health Whitter Hospital, Whittier, California, United States
Yale New Haven Hospital Yale Cancer Center, New Haven, Connecticut, United States
Florida Cancer Specialists - Fort Myers, Fort Myers, Florida, United States
Mayo Clinic Florida, Jacksonville, Florida, United States
Adventist Health System/Sunbelt, Inc d/b/a AdventHealth Orlando, Orlando, Florida, United States
Orlando Health Cancer Institute, Orlando, Florida, United States
University of Illinois Hospital and Health Sciences System, Chicago, Illinois, United States
Greater Baltimore Medical Center, Baltimore, Maryland, United States
Henry Ford Health System, Detroit, Michigan, United States
Mayo Clinic Rochester, Rochester, Minnesota, United States
Summit Medical Group, Florham Park, New Jersey, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Stony Brook University Medical Center, Stony Brook, New York, United States
FirstHealth Cancer Center, Pinehurst, North Carolina, United States
Gabrail Cancer Center, LLC, Canton, Ohio, United States
Providence Portland Medical Center, Portland, Oregon, United States
Saint Lukes University Health Network, Allentown, Pennsylvania, United States
Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina, United States
The West Clinic, PLLC, Germantown, Tennessee, United States
Sarah Cannon Research Institute, Nashville, Tennessee, United States
Texas Oncology - Austin Midtown, Austin, Texas, United States
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
United States Oncology Regulatory Affairs Corporate Office, The Woodlands, Texas, United States
US Oncology Research Investigational Products Center, The Woodlands, Texas, United States
Virginia Oncology Associates, Norfolk, Virginia, United States
Northwest Cancer Specialists - Vancouver, Vancouver, Washington, United States
Aurora Health Care Metro Inc, Milwaukee, Wisconsin, United States
Cemic, Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina
Hospital Italiano de La Plata, La Plata, Buenos Aires, Argentina
Centro Medico Austral, Ciudad Autónoma de Buenos Aires, Distrito Federal, Argentina
Fundacion Ars Medica, San Salvador de Jujuy, Jujuy, Argentina
Clinica Viedma, Viedma, Río Negro, Argentina
Exelsus Oncologia Clinica, San Miguel de Tucuman, Tucuman, Argentina
Fundacion Respirar, Buenos Aires, , Argentina
Hospital Italiano, Capital Federal, , Argentina
Sanatorio Allende, Córdoba, , Argentina
Hospital Privado Universitario de Cordoba, Córdoba, , Argentina
Centro Oncologico Riojano Integral, La Rioja, , Argentina
GenesisCare -North Shore Oncology, St Leonards, New South Wales, Australia
Calvary Mater Newcastle Hospital, Waratah, New South Wales, Australia
The Queen Elizabeth Hospital, Woodville South, South Australia, Australia
Ballarat Health Services, Ballarat, Victoria, Australia
Austin Health, Austin Hospital, Heidelberg, Victoria, Australia
Medizinische Universitaet Graz, Graz, , Austria
Medizinische Universitaet Innsbruck, Innsbruck, , Austria
Landeskrankenhaus Feldkirch, Rankweil, , Austria
Landeskrankenhaus Salzburg, Salzburg, , Austria
Krankenhaus Wiener Neustadt, Wiener Neustadt, , Austria
Universitaetsklinikum Allgemeines Krankenhaus Wien, Wien, , Austria
Universite Catholique de Louvain Cliniques Universitaires Saint Luc, Bruxelles, , Belgium
Grand Hopital de Charleroi, Charleroi, , Belgium
Universitair Ziekenhuis Antwerpen, Edegem, , Belgium
Universitair Ziekenhuis Gent, Gent, , Belgium
Universitair Ziekenhuis Brussel, Jette, , Belgium
Universitair Ziekenhuis Leuven - Campus Gasthuisberg, Leuven, , Belgium
Hopital De Libramont, Libramont, , Belgium
Centre Hospitalier Universitaire de Liege - Sart Tilman, Liege, , Belgium
Algemeen Ziekenhuis Turnhout Campus Sint-Jozef, Turnhout, , Belgium
Hospital Haroldo Juacaba - Instituto do Cancer do Ceara, Fortaleza, Ceará, Brazil
Hospital Sirio Libanes, Brasilia, Distrito Federal, Brazil
Hospital Evangelico de Cachoeiro de Itapemirim, Cachoeiro de Itapemirim, Espírito Santo, Brazil
Personal Oncologia de Precisao e Personalizada, Belo Horizonte, Minas Gerais, Brazil
Liga Norte-Riograndense Contra O Cancer, Natal, Rio Grande Do Norte, Brazil
Hospital das Clinicas de Porto Alegre, Porto Alegre, Rio Grande Do Sul, Brazil
Centro Gaucho Integrado de Oncologia, Hematologia, Ensino e Pesquisa - Hospital Mae de Deus, Porto Alegre, Rio Grande Do Sul, Brazil
Fundacao Pio 12 Hospital de Amor de Barretos, Barretos, São Paulo, Brazil
Instituto do Cancer Arnaldo Vieira de Carvalho, Sao Paulo, São Paulo, Brazil
Sociedade Beneficente de Senhoras Hospital Sirio Libanes, Sao Paulo, São Paulo, Brazil
Fundacao Antonio Prudente AC Camargo Cancer Center, Sao Paulo, São Paulo, Brazil
Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto, São José do Rio Preto, São Paulo, Brazil
Instituto Coi, Rio de Janeiro, , Brazil
Instituto do Cancer do Estado de Sao Paulo Octavio Frias de Oliveira Icesp, São Paulo, , Brazil
Complex Oncology Center - Burgas, Burgas, , Bulgaria
Specialized Hospital for Active Treatment of Oncology - Haskovo EOOD, Haskovo, , Bulgaria
Multiprofile Hospital for Active Treatment - Uni Hospital OOD, Panagyurishte, , Bulgaria
Multiprofile Hospital for Active Treatment Central Onco Hospital OOD, Plovdiv, , Bulgaria
Military Medical Academy Multiprofile Hospital for Active Treatment - Sofia, Sofia, , Bulgaria
Multiprofile Hospital for Active Treatment Serdika EOOD, Sofia, , Bulgaria
London Health Sciences Centre, London, Ontario, Canada
Princess Margaret Cancer Centre, Toronto, Ontario, Canada
Sunnybrook Research Institute Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Jewish General Hospital, Montreal, Quebec, Canada
Centre Hospitalier de L Universite de Montreal, Montréal, Quebec, Canada
CHU de Quebec Hopital de l Enfant Jesus, Quebec, , Canada
Centro De Estudios Clínicos Suecia SpA, Santiago de Chile, Santiago, Chile
Oncocentro Apys, Viña del Mar, Valparaíso, Chile
IC La Serena Research, La Serena, , Chile
Centro de Estudios Clinicos SAGA Spa, Santiago, , Chile
Oncovida, Santiago, , Chile
Icegclinic, Santiago, , Chile
Centro de Estudios Clinicos e Investigaciones Medicas CeCim, Santiago, , Chile
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, Beijing, China
The First Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing, China
Fujian Cancer Hospital, Fuzhou, Fujian, China
Lanzhou University Second Hospital, Lanzhou, Gansu, China
Gansu Provincial Cancer Hospital, Lanzhou, Gansu, China
Gansu Wuwei Tumour Hospital, Wuwei, Gansu, China
The first people's Hospital of Foshan, Foshan, Guangdong, China
Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
Guangdong Provincial Peoples Hospital, Guangzhou, Guangdong, China
Cancer Hospital of Shantou University Medical College, Shantou, Guangdong, China
Guangxi Medical University Cancer Hospital, Nanning, Guangxi, China
The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China
Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China
Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of ScienceandTechnology, Wuhan, Hebei, China
Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China
The First Affiliated Hospital of Henan University of science and Technology, Luoyang, Henan, China
The Cancer Center Union Hospital Tongji Medical College Huazhong University of Science and Tech, Wuhan, Hubei, China
Hubei Cancer Hospital, Wuhan, Hubei, China
The Second Xiangya Hospital of Central South Universiy, Changsha, Hunan, China
Xiangya Hospital of Central South University, Changsha, Hunan, China
Hunan Cancer Hospital, Changsha, Hunan, China
Inner Mongolia Autonomous Region Peoples Hospital, Hohhot, Inner Mongolia, China
The First People's Hospital of Changzhou, Changzhou, Jiangsu, China
Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China
Zhongda Hospital Southeast University, Nanjing, Jiangsu, China
The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China
Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu, China
Northern Jiangsu Peoples Hospital, Yangzhou, Jiangsu, China
The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China
General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China
Shaanxi Provincial Peoples Hospital, Xian, Shaanxi, China
Qilu Hospital of Shandong University, Jinan, Shandong, China
The Affiliated Cancer Hospital of Shandong First Medical University, Jinan, Shandong, China
Affiliated Hospital of Jining Medical University, Jining, Shandong, China
Ruijin Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China
Zhongshan Hospital Fudan University, Shanghai, Shanghai, China
Changzhi Peoples Hospital, Changzhi, Shanxi, China
Linfen Central Hospital, Linfen, Shanxi, China
Sichuan Cancer Hospital, Chengdu, Sichuan, China
West China Hospital of Sichuan University, Chengdu, Sichuan, China
The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China
Yunnan Cancer Hospital, Kunming, Yunnan, China
Sir Run Run Shaw Hospital Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Taizhou Hospital of Zhejiang Province, Linhai, Zhejiang, China
Fakultni nemocnice Hradec Kralove, Hradec Kralove, , Czechia
Fakultni nemocnice Olomouc, Olomouc, , Czechia
Fakultni nemocnice Kralovske Vinohrady, Praha 10, , Czechia
Vseobecna fakultni nemocnice v Praze, Praha 2, , Czechia
Fakultni Thomayerova nemocnice, Praha 4, , Czechia
Centre Hospitalier Universitaire Amiens Picardie - Hopital Sud, Amiens Cedex 1, , France
Centre Hospitalier Régional Universitaire de Besançon, Hôpital Jean Minjoz, Besançon, , France
Institut Bergonie, Bordeaux, , France
Centre Hospitalier Universitaire de Brest - Cavale Blanche, Brest, , France
Centre Hospitalier Universitaire de Clermont Ferrand, Hôpital Estaing, Clermont-Ferrand cedex 1, , France
Centre Hospitalier Régional Universitaire de Lille - Hôpital Claude Huriez, Lille, , France
Centre Hospitalier Universitaire de Limoges - Hopital Dupuytren, Limoges Cedex, , France
Centre Leon Berard, Lyon cedex 8, , France
Centre Antoine Lacassagne, Nice, , France
Hôpital Saint Louis, Paris Cedex 10, , France
Institut Mutualiste Montsouris, Paris Cedex 14, , France
Hôpital Européen Georges Pompidou, Paris, , France
Centre Hospitalier Universitaire de Rouen, Rouen Cedex, , France
Centre Rene Gauducheau - Institut de Cancerologie de l Ouest, Saint Herblain, , France
Centre Hospitalier Universitaire Nord de Saint Etienne - Hôpital Nord, Saint Priest en Jarez, , France
Institut de cancerologie Strasbourg Europe, Strasbourg cedex, , France
Centre Hospitalier Universitaire de Toulouse - Hopital Rangueil, Toulouse Cedex 9, , France
Institut Gustave Roussy, Villejuif, , France
Charite - Universitaetsmedizin Berlin, Campus Virchow, Berlin, , Germany
Universitaetsklinikum Dresden, Dresden, , Germany
Krankenhaus Nordwest GmbH, Frankfurt am Main, , Germany
Haematologisch Onkologische Praxis Eppendorf, Hamburg, , Germany
Medizinische Hochschule Hannover, Hannover, , Germany
Universitaetsklinikum Schleswig-Holstein, Kiel, , Germany
Universitaetsklinikum Leipzig, Leipzig, , Germany
Regional Kliniken Holding Klinikum Ludwigsburg, Ludwigsburg, , Germany
Johannes Gutenberg Universitaet Mainz, Mainz, , Germany
Universitaetsmedizin Mannheim, Mannheim, , Germany
Klinikum der LMU Muenchen, Muenchen, , Germany
Klinikum rechts der Isar der TUM, Muenchen, , Germany
Universitaetsklinikum der Eberhard Karls Universitaet Tuebingen, Tuebingen, , Germany
Universitaetsklinikum Ulm, Ulm, , Germany
Klinikum der Stadt Wolfsburg, Wolfsburg, , Germany
Prince of Wales Hospital, Shatin, New Territories, , Hong Kong
Semmelweis Egyetem, Budapest, , Hungary
Del-pesti Centrumkorhaz - Orszagos Hematologiai es Infektologiai Intezet, Budapest, , Hungary
Orszagos Onkologiai Intezet, Budapest, , Hungary
Debreceni Egyetem Klinikai Kozpont, Debrecen, , Hungary
Szabolcs-Szatmar-Bereg Varmegyei Oktatokorhaz Nyiregyhazi Josa Andras Tagkorhaz, Nyiregyhaza, , Hungary
Tolna Varmegyei Balassa Janos Korhaz, Szekszard, , Hungary
Jasz-Nagykun-Szolnok Varmegyei Hetenyi Geza Korhaz-Rendelointezet, Szolnok, , Hungary
Komarom-Esztergom Varmegyei Szent Borbala Korhaz, Tatabanya, , Hungary
Rambam Health Care Campus, Haifa, , Israel
Shaare Zedek Medical Center, Jerusalem, , Israel
Hadassah Ein-Kerem Medical Center, Jerusalem, , Israel
Sheba Medical Center, Ramat Gan, , Israel
Tel-Aviv Sourasky Medical Center, Tel Aviv, , Israel
Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona, Ancona, , Italy
Azienda Socio Sanitaria Territoriale Papa Giovanni xxiii, Bergamo, , Italy
Ente Ospedaliero IRCCS Saverio De Bellis, Castellana Grotte, , Italy
Azienda Socio Sanitaria Territoriale di Cremona, Cremona, , Italy
Azienda Ospedaliero Universitaria Careggi, Firenze, , Italy
Ospedale Policlinico San Martino IRCCS, Genova, , Italy
IRCCS Ospedale San Raffaele, Milano, , Italy
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, , Italy
Azienda Ospedaliero Universitaria Luigi Vanvitelli, Napoli, , Italy
Istituto Oncologico Veneto IRCCS, Padova, , Italy
Azienda Ospedaliera Universitaria Pisana, Pisa, , Italy
Nagoya University Hospital, Nagoya-shi, Aichi, Japan
Chiba Cancer Center, Chiba-shi, Chiba, Japan
National Cancer Center Hospital East, Kashiwa-shi, Chiba, Japan
National Hospital Organization Shikoku Cancer Center, Matsuyama-shi, Ehime, Japan
National Hospital Organization Kyushu Cancer Center, Fukuoka-shi, Fukuoka, Japan
Gifu University Hospital, Gifu-shi, Gifu, Japan
Hokkaido University Hospital, Sapporo, Hokkaido, Japan
Hyogo Cancer Center, Akashi-shi, Hyogo, Japan
Kobe City Medical Center General Hospital, Kobe-shi, Hyogo, Japan
Yokohama City University Medical Center, Yokohama-shi, Kanagawa, Japan
Kanagawa Prefectural Hospital Organization Kanagawa Cancer Center, Yokohama-shi, Kanagawa, Japan
Niigata Cancer Center Hospital, Niigata-shi, Niigata, Japan
Kansai Medical University Hospital, Hirakata-shi, Osaka, Japan
Osaka International Cancer Institute, Osaka-shi, Osaka, Japan
Kindai University Hospital, Osakasayama-shi, Osaka, Japan
Osaka University Hospital, Suita-shi, Osaka, Japan
Saitama Cancer Center, Kitaadachi-gun, Saitama, Japan
Shizuoka Cancer Center, Sunto-gun, Shizuoka, Japan
National Cancer Center Hospital, Chuo-ku, Tokyo, Japan
The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan
Kyungpook National University Chilgok Hospital, Daegu, , Korea, Republic of
Chungnam National University Hospital, Daejeon, , Korea, Republic of
National Cancer Center, Goyang-si Gyeonggi-do, , Korea, Republic of
Jeonbuk National University Hospital, Jeonju-si, Jeollabuk-do, , Korea, Republic of
Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, , Korea, Republic of
Korea University Anam Hospital, Seoul, , Korea, Republic of
Seoul National University Hospital, Seoul, , Korea, Republic of
Kangbuk Samsung Hospital, Seoul, , Korea, Republic of
Severance Hospital Yonsei University Health System, Seoul, , Korea, Republic of
Asan Medical Center, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
The Catholic University of Korea Seoul St Marys Hospital, Seoul, , Korea, Republic of
Korea University Guro Hospital, Seoul, , Korea, Republic of
Beskidzkie Centrum Onkologii Szpital Miejski imienia Jana Pawla Drugiego, Bielsko-Biala, , Poland
Narodowy Instytut Onkologii im M Sklodowskiej-Curie Panstwowy Instytut Badawczy Oddzial w Gliwicach, Gliwice, , Poland
Przychodnia Lekarska Komed Roman Karaszewski, Konin, , Poland
Samodzielny Publiczny Szpital Kliniczny Nr 1, Lublin, , Poland
Szpital Kliniczny Ministerstwa Spraw Wewnetrznych i Administracji, Olsztyn, , Poland
Mazowiecki Szpital Wojewodzki im Sw Jana Pawla II w Siedlcach spzoo, Siedlce, , Poland
Centrum Medyczne Pratia Poznan, Skorzewo, , Poland
Samodzielny Publiczny Szpital Kliniczny Nr 1 Pomorskiego Uniwersytetu Medycznego w Szczecinie, Szczecin, , Poland
Lux med onkologia sp zoo szpital szamocka, Warszawa, , Poland
Narodowy Instytut Onkologii im Marii Sklodowskiej-Curie Panstwowy Instytut Badawczy, Warszawa, , Poland
MTZ Clinical Research powered by Pratia, Warszawa, , Poland
Uniwersytecki Szpital Kliniczny im Jana Mikulicza-Radeckiego we Wroclawiu, Wroclaw, , Poland
Unidade Local de Saude de Braga, EPE, Braga, , Portugal
Unidade Local de Saude do Alto Ave, EPE, Guimaraes, , Portugal
Hospital da Luz, SA, Lisboa, , Portugal
Unidade Local de Saude de Santa Maria, EPE - Hospital de Santa Maria, Lisboa, , Portugal
Unidade Local de Saude de Matosinhos, EPE - Hospital Pedro Hispano, Matosinhos, , Portugal
Hospital Cuf porto, Porto, , Portugal
Unidade Local de Saude de Sao Joao, EPE - Hospital de Sao Joao, Porto, , Portugal
Institutul Clinic Fundeni, Bucharest, , Romania
Institutul Oncologic Prof Dr Ion Chiricuta Cluj-Napoca, Cluj Napoca, , Romania
Institutul Regional de Gastroenterologie si Hepatologie Prof Dr Octavian Fodor, Cluj-Napoca, , Romania
Centrul de Oncologie Sf Nectarie SRL, Craiova, , Romania
Institutul Regional de Oncologie Iasi, Iasi, , Romania
SC Oncomed SRL, Timisoara, , Romania
National University Hospital, Singapore, , Singapore
National Cancer Centre Singapore, Singapore, , Singapore
Hospital Universitario Virgen del Rocio, Sevilla, Andalucía, Spain
Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain
Hospital del Mar, Barcelona, Cataluña, Spain
Hospital Universitari Vall d Hebron, Barcelona, Cataluña, Spain
Institut Catala d Oncologia Hospitalet Hospital Duran i Reynals, Hospitalet de Llobregat, Cataluña, Spain
Hospital General Universitario de Elche, Elche, Comunidad Valenciana, Spain
Hospital Clinico Universitario de Valencia, Valencia, Comunidad Valenciana, Spain
Complexo Hospitalario Universitario A Coruña Hospital Teresa Herrera, A Coruña, Galicia, Spain
Hospital Universitario de Navarra, Pamplona, Navarra, Spain
Hospital Universitario Ramon y Cajal, Madrid, , Spain
Hospital Clinico San Carlos, Madrid, , Spain
Hospital Universitario 12 de Octubre, Madrid, , Spain
Universitaetsspital Basel, Basel, , Switzerland
Inselspital Bern, Bern, , Switzerland
Kantonsspital Graubuenden, Chur, , Switzerland
Hopitaux Universitaires de Geneve, Geneve, , Switzerland
Onkozentrum Zuerich, Zurich, , Switzerland
Universitaetsspital Zuerich, Zurich, , Switzerland
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, , Taiwan
China Medical University Hospital, Taichung, , Taiwan
National Cheng Kung University Hospital, Tainan, , Taiwan
Taipei Veterans General Hospital, Taipei, , Taiwan
Tri-Service General Hospital, Taipei, , Taiwan
Chulabhorn Hospital, Bangkok, , Thailand
Siriraj Hospital, Bangkok, , Thailand
Maharaj Nakorn Chiang Mai Hospital, Chiang Mai, , Thailand
Chiangrai Prachanukroh Hospital, Chiang Rai, , Thailand
Prince of Songkla Hospital, Songkhla, , Thailand
Addenbrookes Hospital, Cambridge, , United Kingdom
University Hospital Coventry, Coventry, , United Kingdom
Ninewells Hospital and Medical School, Dundee, , United Kingdom
Guys Hospital, London, , United Kingdom
Christie Hospital, Manchester, , United Kingdom
Mount Vernon Cancer Centre, Northwood, , United Kingdom
Torbay Hospital, Torquay, , United Kingdom
Name: MD
Affiliation: Amgen
Role: STUDY_DIRECTOR