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Brief Title: Dovitinib for Gastric Cancer With FGFR2 Amplification: GASDOVI-1
Official Title: A Phase II Trial of Dovitinib Monotherapy as Salvage Treatment in Patients With Metastatic or Unresectable Gastric Cancer Harboring FGFR2(Fibroblast Growth Factor Receptor 2) Amplification After Failure of First or Second Line Chemotherapy
Study ID: NCT01719549
Brief Summary: This is a single-center, prospective, single-arm, open-label phase II study
Detailed Description: In this study, we will evaluate the efficacy and safety of TKI258(Dovitinib) monotherapy as a salvage chemotherapy after failure of standard first or second-line chemotherapy in metastatic or unresectable gastric cancer harboring FGFR2 amplification.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Asan Medical Center, Seoul, , Korea, Republic of
Name: Yoon-Koo Kang, PhD
Affiliation: Asan Medical Center
Role: PRINCIPAL_INVESTIGATOR