Spots Global Cancer Trial Database for An Investigational Study of Immunotherapy Combinations With Chemotherapy in Patients With Gastric or Gastroesophageal Junction (GEJ) Cancers
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Trial Identification
Brief Title: An Investigational Study of Immunotherapy Combinations With Chemotherapy in Patients With Gastric or Gastroesophageal Junction (GEJ) Cancers
Official Title: A Randomized, Open-label, Phase II Clinical Trial of Relatlimab (Anti-LAG-3) and Nivolumab in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy as First-Line Treatment in Patients With Gastric or Gastroesophageal Junction Adenocarcinoma
Study ID: NCT03662659
Study Description
Brief Summary: The purpose of this study is to determine the efficacy and safety of investigational drug relatlimab plus nivolumab in combination with chemotherapy in participants with unresectable, untreated, locally advanced or metastatic gastric or GEJ cancer.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Local Institution - 0049, Clovis, California, United States
Local Institution - 0064, Duarte, California, United States
Scripps Clinic, La Jolla, California, United States
Local Institution - 0040, Los Angeles, California, United States
Hoag Memorial Hospital Presbyterian, Newport Beach, California, United States
Local Institution - 0041, Orange, California, United States
Local Institution - 0077, Santa Monica, California, United States
Local Institution - 0056, Aurora, Colorado, United States
Local Institution - 0062, New Haven, Connecticut, United States
Local Institution - 0050, Hackensack, New Jersey, United States
Local Institution - 0054, Dallas, Texas, United States
Virginia Cancer Institute, Richmond, Virginia, United States
Local Institution - 0052, Seattle, Washington, United States
Local Institution - 0010, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina
Local Institution - 0009, Buenos Aires, Ciudad Autónoma De Buenos Aires, Argentina
Local Institution - 0011, San Miguel de Tucumán, Tucumán, Argentina
Local Institution - 0078, Caba, , Argentina
Local Institution - 0027, Westmead, New South Wales, Australia
Local Institution - 0007, Herston, Queensland, Australia
Local Institution - 0003, Heidelberg, Victoria, Australia
Local Institution - 0029, Malvern, Victoria, Australia
Local Institution - 0008, Shepparton, Victoria, Australia
Local Institution - 0005, Murdoch, Western Australia, Australia
Local Institution - 0028, Bedford Park, , Australia
Local Institution - 0090, Graz, , Austria
Local Institution - 0089, Wien, , Austria
Local Institution - 0091, Bruxelles, , Belgium
Local Institution - 0092, Leuven, , Belgium
Local Institution - 0024, Kelowna, British Columbia, Canada
Local Institution - 0063, Halifax, Nova Scotia, Canada
Local Institution - 0070, Toronto, Ontario, Canada
Local Institution - 0055, Trois-Rivieres, Quebec, Canada
Local Institution - 0095, Quebec, , Canada
Local Institution - 0002, Rancagua, L.g.bernardoohiggins, Chile
Local Institution - 0080, Santiago, Metropolitana, Chile
Local Institution - 0001, Vina del Mar, Valparaiso, Chile
Local Institution - 0079, Santiago, , Chile
Local Institution - 0031, Brno, , Czechia
Local Institution - 0030, Olomouc, , Czechia
Local Institution - 0047, Avignon Cedex 9, , France
Local Institution - 0073, Besancon Cedex, , France
Local Institution - 0045, Dijon, , France
Local Institution - 0071, Montpellier, , France
Local Institution - 0043, Paris, , France
Local Institution - 0072, Paris, , France
Local Institution - 0046, Rouen Cedex, , France
Local Institution - 0083, Cologne, , Germany
Local Institution - 0082, Dresden, , Germany
Local Institution - 0017, Essen, , Germany
Local Institution - 0081, Essen, , Germany
Local Institution - 0014, Frankfurt, , Germany
Local Institution - 0018, Hamburg, , Germany
Local Institution - 0012, Hannover, , Germany
Local Institution - 0013, Heidelberg, , Germany
Local Institution - 0015, Mannheim, , Germany
Local Institution - 0016, Marburg, , Germany
IRCCS Istituto Nazionale Tumori Milano, Milano, , Italy
Local Institution - 0020, Milan, , Italy
Local Institution - 0021, Roma, , Italy
Local Institution - 0088, Bergen, , Norway
Local Institution - 0086, Oslo, , Norway
Local Institution - 0087, Trondheim, , Norway
Local Institution - 0093, Warszawa, , Poland
Local Institution - 0067, San Juan, , Puerto Rico
Local Institution - 0038, Singapore, , Singapore
Local Institution - 0058, Madrid, M, Spain
Local Institution - 0099, Badajoz, , Spain
Local Institution - 0098, Barcelona, , Spain
Local Institution - 0061, Barcelona, , Spain
Local Institution - 0059, Bilbao, , Spain
Local Institution - 0057, Madrid, , Spain
Local Institution - 0060, Zaragoza, , Spain
Local Institution - 0075, Manchester, Greater Manchester, United Kingdom
Local Institution - 0035, Nottingham, Nottinghamshire, United Kingdom
Local Institution - 0032, Coventry, West Midlands, United Kingdom
Local Institution - 0036, Lancaster, , United Kingdom
Local Institution - 0034, London, , United Kingdom
Local Institution - 0069, Northwood, , United Kingdom
Local Institution - 0033, Southampton, , United Kingdom
Contact Details
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR
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