Spots Global Cancer Trial Database for Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
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Trial Identification
Brief Title: Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
Official Title: An Open-Label, Multi-Drug, Multi-Centre, Phase II Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
Study ID: NCT05702229
Conditions
Study Description
Brief Summary: This is a Phase II, open-label, multi-drug, multi-centre study designed to assess the efficacy, safety, tolerability, pharmacokinetics, and immunogenicity of novel combination therapies in participants with locally advanced unresectable or metastatic gastric or GEJ adenocarcinoma.
Detailed Description: Approximately 240 participants will be assigned across 6 substudies, with approximately 40 evaluable participants of the confirmed recommend dose by SRC for study intervention in each corresponding substudy.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Research Site, Los Angeles, California, United States
Research Site, Los Angeles, California, United States
Research Site, Baton Rouge, Louisiana, United States
Research Site, Grand Rapids, Michigan, United States
Research Site, Bronx, New York, United States
Research Site, New Hyde Park, New York, United States
Research Site, New York, New York, United States
Research Site, New York, New York, United States
Research Site, Shirley, New York, United States
Research Site, Pittsburgh, Pennsylvania, United States
Research Site, Beijing, , China
Research Site, Hangzhou, , China
Research Site, Hangzhou, , China
Research Site, Harbin, , China
Research Site, Hefei, , China
Research Site, Kunming, , China
Research Site, Wuhan, , China
Research Site, Yinchuan, , China
Research Site, Zhengzhou, , China
Research Site, Kashiwa, , Japan
Research Site, Sunto-gun, , Japan
Research Site, Tokyo, , Japan
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Barcelona, , Spain
Research Site, Elche(Alicante), , Spain
Research Site, L'Hospitalet de Llobregat, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Santander, , Spain
Research Site, Hsinchu, , Taiwan
Research Site, Kaohsiung, , Taiwan
Research Site, Taichung, , Taiwan
Research Site, Tainan City, , Taiwan
Research Site, Taipei, , Taiwan
Research Site, Taipei, , Taiwan
Research Site, Taoyuan City, , Taiwan
Research Site, Edinburgh, , United Kingdom
Research Site, Leeds, , United Kingdom
Research Site, London, , United Kingdom
Research Site, Oxford, , United Kingdom
Contact Details
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