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Brief Title: Study of Autologous Tumor Lysate-pulsed D-CIK Combined With Chemotherapy for Gastric Cancer
Official Title: Randomized,Controlled,Multicenter Study of Autologous Tumor Lysate-pulsed Dendritic and Cytokine-induced Killer Cells(Ag-D-CIK) Combined With Chemotherapy for Gastric Cancer.
Study ID: NCT02215837
Brief Summary: The purpose of this study is to evaluate the safety and efficacy of chemotherapy combined with autologous tumor Lysate-pulsed dendritic with cytokine-induced killer cell (Ag-D-CIK) for gastric cancer.
Detailed Description: 40 patients with stage Ⅰ~Ⅲ Gastric Cancer,who had received surgery and kept their tumor tissue,will be randomly divided into group A(receive Ag-D-CIK treatment and chemotherapy) or group B(just receive chemotherapy),and the randomize ratio will be 1:1. Patients in group A will receive 3 cycles of Ag-D-CIK treatment (every 1 months) and 4 cycles of chemotherapy (every 2 weeks).Patients in group B will receive only 4 cycles chemotherapy(every 2 weeks).
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Affiliated Tumor Hospital of Guangzhou Medical University Immunotherapy center, Guangzhou, Guangdong, China
Jingzhou Central Hospital Immunotherapy center, Jingzhou, Hubei, China
Name: Hai Y Liu, Professor
Affiliation: Affiliated Tumor Hospital of Guangzhou Medical University immunotherapy center
Role: PRINCIPAL_INVESTIGATOR