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Spots Global Cancer Trial Database for A Study to Evaluate Rivoceranib Plus Best Supportive Care Compared to Placebo Plus Best Supportive Care in Participants With Gastric Cancer

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Trial Identification

Brief Title: A Study to Evaluate Rivoceranib Plus Best Supportive Care Compared to Placebo Plus Best Supportive Care in Participants With Gastric Cancer

Official Title: A Prospective, Randomized, Double-Blinded, Placebo-Controlled, Multinational, Multicenter, Parallel-group, Phase III Study to Evaluate the Efficacy and Safety of Apatinib Plus Best Supportive Care (BSC) Compared to Placebo Plus BSC in Patients With Advanced or Metastatic Gastric Cancer

Study ID: NCT03042611

Interventions

Rivoceranib
Placebo

Study Description

Brief Summary: The purpose of this study is to evaluate the efficacy and safety of rivoceranib plus best supportive care (BSC) compared to placebo plus BSC in participants with advanced or metastatic gastric cancer (GC).

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Mayo Clinic Phoenix, Scottsdale, Arizona, United States

Highlands Oncology Group, Rogers, Arkansas, United States

Karmanos Cancer Institute, Detroit, Michigan, United States

Mayo Clinic Cancer Center, Rochester, Minnesota, United States

Hudson Valley Cancer Centre, Hawthorne, New York, United States

Centre Hospitalier Franco-Britannique; Oncologie Médicale, Levallois-Perret, , France

Centre Leon-Berard (CLB), Lyon, , France

Institut Regional du Cancer Montpellier (ICM), Montpellier, , France

Centre Antoine-Lacassagne, Nice, , France

Institut Gustave Roussy, Villejuif, , France

Charite - Universitaetsmedizin Berlin - Medizinische Klinik mit Schwerpunkt Haematologie, Onkologie und Tumorimmunologie, Berlin, , Germany

"Institut für Klinisch-Onkologische Forschung (IKF) Krankenhaus Nordwest gGmbH UCT - Universitäres Centrum für Tumorerkrankungen Frankfurt, Frankfurt, , Germany

Facharztzentrum Eppendorf - Haematologisch-Onkologische Praxis Eppendorf (HOPE), Hamburg, , Germany

Universitätsklinik Marburg, Klinik fur Innere Medizin, Schwerpunkt Haematologie, Onkologie und Immunologie, Marburg, , Germany

Magna Graecia University- Department of Experimental and Clinical Medicine, Catanzaro, , Italy

U.O Di Oncologia Ospedale Degli Infermi, Faenza, , Italy

Fondazione IRCCS-Istituto Nazionale Tumori, Milano, , Italy

Policlinico di Modena-Azienda Ospedaliero Universitaria di Modena.Oncologia ed Ematologia., Modena, , Italy

Veneto Oncology Institute (IOV-IRCCS), Melanoma & Esophageal Oncology Unit, Padova, , Italy

Ospedale di Piacenza - Oncology and heamatology, Piacenza, , Italy

Ospedale "Felice Lotti", Pontedera, , Italy

IRCCS/Arcispedale Santa Maria Nuova, Reggio Emilia, , Italy

Rimini Hospital, Rimini, , Italy

Ospedali Riuniti di Ancona - SOD Clinica Oncologica, Torrette, , Italy

Hyogo Cancer Center, Hyogo, Akasi-city, Japan

Chiba Cancer Center, Chiba, Chiba City, Japan

National Cancer Center Hospital, Tokyo, Chuo-ku, Japan

Kyushu University Hospital, Fukuoka, Higashi-ku, Japan

National Cancer Center Hospital East, Chiba, Kashiwa, Japan

St. Marianna University School of Medicine Hospital, Kanagawa, Kawasaki-shi, Japan

Saitama Cancer Center, Saitama, Kitaadachi-gun, Japan

Japan Community Health Care Organization Kyushu Hospital, Fukuoka, Kitakyushu-shi, Japan

The Cancer Institute Hospital of Japanese Foundation For Cancer Research, Tokyo, Koto-ku, Japan

National Hospital Organization Shikoku Cancer Center, Ehime, Matsuyama, Japan

Saku Central Hospital Advanced Care Center, Nagano, Saku-shi, Japan

Hokkaido University Hospital, Hokkaido, Sapporo, Japan

Keio University Hospital, Tokyo, Shinjuku-ku, Japan

Osaka University Hospital, Osaka, Suita, Japan

Aichi Cancer Center Hospital, Nagoya, , Japan

Hallym University Sacred Heart Hospital, Anyang-si, Gyeonggi-do, Korea, Republic of

National Cancer Center, Goyang-si, Gyeonggi-do, Korea, Republic of

Ajou University Hospital, Suwon-si, Gyonggi-do, Korea, Republic of

Inje University Haeundae Paik Hospital, Busan, , Korea, Republic of

Dong-A University Hospital, Busan, , Korea, Republic of

Pusan National University Hospital, Busan, , Korea, Republic of

Chungbuk National University Medical Center, Chuncheon, , Korea, Republic of

Chungbuk National University Hospital, Chungbuk, , Korea, Republic of

Kyungpook National University Medical Center, Daegu, , Korea, Republic of

Keimyung University Dongsan Medical Center, Daegu, , Korea, Republic of

Yeungnam University Medical Center, Daegu, , Korea, Republic of

Chungnam National University Hospital, Daejeon, , Korea, Republic of

Seoul National University Bundang Hospital, Gyeonggi-do, , Korea, Republic of

Gachon University Gil Medical Center, Incheon, , Korea, Republic of

Korea University Anam Hospital, Seoul, , Korea, Republic of

Severence Hospital, Yonsei University Health System, Seoul, , Korea, Republic of

Veterans Health Service (VHS) Medical Center, Seoul, , Korea, Republic of

ASAN Medical Center, Seoul, , Korea, Republic of

Gangnam Severance Hospital, Seoul, , Korea, Republic of

Samsung Medical Center, Seoul, , Korea, Republic of

Korea University Guro Hospital, Seoul, , Korea, Republic of

Ulsan University Hospital, Ulsan, , Korea, Republic of

Szpital Uniwersytecki w Krakowie, Odział Kliniczny Onkologii, Kraków, , Poland

Centrum Onkologii-Instytut im. Marii Skłodowskiej-Curie, Klinika Gastroenterologii Onkologicznej, Warszawa, , Poland

Saint Constantin Hospital (TEO HEALTH SA), Brasov, , Romania

Institutul Oncologic "Prof. Dr. Ion Chiricuta" Cluj-Napoca, Sectia de Radioterapie I, Cluj-Napoca, , Romania

S.C. Medisprof S.R.L., Cluj-Napoca, , Romania

Centrul de Oncologie "Sf. Nectarie", Sectia de Oncologie Medicala, Craiova, , Romania

State Budgetary Healthcare Institution of Arkhangelsk Region "Arkhangelsk Clinical Oncology Dispensary", Arkhangelsk, , Russian Federation

State Healthcare Institution "Kursk Regional Clinical Oncology Dispensary", Kursk, , Russian Federation

Omsk regional clinical oncology center, Omsk, , Russian Federation

Budgetary Healthcare Institution of Orel Region "Orel Oncology Dispensary", Oryol, , Russian Federation

State Budgetary Healthcare Institution of Stavropol Territory "Pyatigorsk Oncology Dispensary", Pyatigorsk, , Russian Federation

Ogarev Mordovia State University, Saransk, , Russian Federation

Federal State Budgetary Educational Institution of Higher Education "Academician I.P. Pavlov First St. Petersburg State Medical University" of the Ministry of Heaithcare of the Russian Federation, St. Petersburg, , Russian Federation

State Budgetary Healthcare Institution "Republican Clinical Oncology Dispensary", Ufa, , Russian Federation

Taipei Veterans General Hospital, Taipei, Beitou Dist, Taiwan

Chang Gung Memorial Hospital - Linko Branch, Taoyuan, Kuei Shan Hsiang, Taiwan

Chi Mei Medical Center - LiouYing Branch, Tainan, Liuying DIst, Taiwan

Chang Gung Memorial Hospital - Kaohsiung Branch, Kaohsiung, Niaosong Dist, Taiwan

Kaohsiung Medical University Hospital, Kaohsiung, Sanmin Dist, Taiwan

China Medical University Hospital, Taichung, Taichung City, Taiwan

National CHeng Kung University Hospital, Tainan, Tainan City, Taiwan

National Taiwan University Hospital, Taipei, Zhongzheng Dist, Taiwan

Dnipropetrovsk Medical Academy, Department of Oncology, Dnipro, , Ukraine

Communal Institution "Ivano-Frankivsk Regional Oncological Center", Ivano-Frankivsk, , Ukraine

Communal Institution "Kharkiv Regional Clinical Oncology Center ", Chemotherapy department #1, Medical Academy of Postgraduate Education, Oncology and Pediatric Oncology, Kharkiv, , Ukraine

Kherson Regional Oncological Dispensary, Kherson, , Ukraine

Municipal Institution Kryvyi Rig Oncology Dispensary", Chemotherapy Department, Kryvyi Rih, , Ukraine

Municipal Institution "Kyiv City Clinical Oncological Center", Kyiv, , Ukraine

Communal Institution "Transcarpathian Regional Clinical Oncological Center", Uzhhorod, , Ukraine

Communal Institution "Vinnytsia Regional Clinical Oncology Dispensary", Vinnytsia, , Ukraine

State institution "Zaporizhzhia Medical Academy of Postgraduate Education MOH Ukraine", Department of oncology based on Municipal Institution "Zaporizhzhia Regional Clinical Oncology Dispensary" Zaporizhzhia Regional Assembly, Zaporizhzhia, , Ukraine

Royal Marsden Hospital London, London, , United Kingdom

The Christie NHS Foundation Trust, Manchester, , United Kingdom

Royal Marsden Hospital Surrey, Sutton, , United Kingdom

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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