Spots Global Cancer Trial Database for Clinical Study of Taurine Combined With Neoadjuvant Chemo-Immunotherapy for Treatment of Locally Advanced Gastric Cancer
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Trial Identification
Brief Title: Clinical Study of Taurine Combined With Neoadjuvant Chemo-Immunotherapy for Treatment of Locally Advanced Gastric Cancer
Official Title: A Prospective, Randomized Controlled Clinical Study of The Efficacy and Safety of Taurine Combined With Serplulimab and Chemotherapy Versus Serplulimab Combined With Chemotherapy for Treatment of Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
Study ID: NCT06128252
Conditions
Study Description
Brief Summary: This project aims to evaluate the efficacy and safety of oral taurine supplementation combined with PD-1 inhibitor (serplulimab) and chemotherapy in inducing systemic CD8+ T cell responses and achieving improved gastric cancer patient outcomes than with serplulimab and chemotherapy alone.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Tang-Du Hospital, Xi'an, Shaanxi, China
Contact Details
Name: Xin Wang, MD, PhD
Affiliation: Tang-Du Hospital
Role: STUDY_DIRECTOR
Name: Xiaodi Zhao, MD, PhD
Affiliation: Xi-Jing Hospital
Role: PRINCIPAL_INVESTIGATOR
Name: Yuanyuan Lu, MD, PhD
Affiliation: Xi-Jing Hospital
Role: PRINCIPAL_INVESTIGATOR
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