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Brief Title: Clinical Study of Taurine Combined With Sintilimab and Chemotherapy for Treatment of Advanced Gastric Cancer
Official Title: A Prospective, Randomized Controlled Clinical Study of The Efficacy and Safety of Taurine Combined With Sintilimab and Chemotherapy Versus Sintilimab Combined With Chemotherapy for Treatment of Advanced Gastric Cancer
Study ID: NCT06123455
Brief Summary: This project aims to evaluate the efficacy and safety of oral taurine supplementation combined with PD-1 inhibitor (sintilimab) and chemotherapy in inducing systemic CD8+ T cell responses and achieving improved gastric cancer patient outcomes than with sintilimab and chemotherapy alone.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Tang-Du Hospital, Xi'an, Shaanxi, China
Name: Xin Wang, MD, PhD
Affiliation: Tang-Du Hospital
Role: STUDY_DIRECTOR
Name: Xiaodi Zhao, MD, PhD
Affiliation: Xi-Jing Hospital
Role: PRINCIPAL_INVESTIGATOR
Name: Yuanyuan Lu, MD, PhD
Affiliation: Xi-Jing Hospital
Role: PRINCIPAL_INVESTIGATOR