Spots Global Cancer Trial Database for Adjuvant Chemotherapy With S-1 Plus Oxaliplatin Versus S-1 Alone in Locally Advanced Gastric Cancer
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Trial Identification
Brief Title: Adjuvant Chemotherapy With S-1 Plus Oxaliplatin Versus S-1 Alone in Locally Advanced Gastric Cancer
Official Title: A Randomized, Multicentral, Controlled, Phase III Study to Compare Adjuvant Chemotherapy With S-1 Plus Oxaliplatin to S-1 Alone After Curative Distal Gastrectomy in Locally Advanced Gastric Cancer
Study ID: NCT02867839
Conditions
Study Description
Brief Summary: The purpose of the study is to evaluate the efficacy and safety of S-1 plus Oxaliplatin versus S-1 only as adjuvant chemotherapy after curative distal gastrectomy in patients with locally advanced gastric cancer.
Detailed Description: The study is a multi-central, controlled, randomized Phase III trial. The protocol has been approved by the Ethics Committee of Beijing Cancer Hospital. The primary endpoint is the 3-year progression-free survival (PFS) rate. The secondary endpoints are the overall survival (OS) and safety.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Cancer Hospital Chinese Acadamy of Medical Sciences, Beijing, Beijing, China
Peking University First Hospital, Beijing, Beijing, China
Peking University People's Hospital, Beijing, Beijing, China
Beijing Friendship Hospital, Beijing, Beijing, China
Xuanwu Hospital, Beijing, Beijing, China
Beijing Cancer Hospital, Beijing, Beijing, China
Beijing Hospital, Beijing, Beijing, China
Chinese PLA General Hospital, Beijing, Beijing, China
Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China
Nanjing General Hospital, Nanjing, Jiangsu, China
The First Affiliated Hospital of Daliang Medical University, Daliang, Liaoning, China
Qilu Hospital of Shandong University, Jinan, Shandong, China
Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China
The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
Contact Details
Name: Jiafu Ji, MD
Affiliation: Peking University Cancer Hospital & Institute
Role: STUDY_CHAIR
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