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Brief Title: Lymph Node 14v Dissection in Clinical Stage T3N+, T4N+ of Gastric Cancer
Official Title: A Multicenter Randomized Controlled Trial of D2 Versus D2 + Lymph Node 14v Dissection in Clinical Stage T3N+, T4N+ of Gastric Cancer (14VIGTORY Trial)
Study ID: NCT03264807
Brief Summary: The purpose of this study is to compare the survival rate according to the presence or absence of 14v lymph node dissection.
Detailed Description: The purpose of this study is to compare the survival rate according to the presence or absence of 14v lymph node dissection. Actually, if the 14v lymph node metastasis is suspected before surgery, it is excluded from the study. In a retrospective study conducted in our hospital, we compared the patients with the 14v lymphadenectomy group and those without the 14v lymphadenectomy group, the survival rate of the 14v lymphadenectomy group was 11% higher than that of the 14v non-lymphadenectomy group.Previous studies have suggested that the presence of metastatic lymph nodes in the 14v lymph node is not good and that removal of the 14v lymph node does not affect prognosis. However, if the lymph node is a continuous tissue and the transition to the 14v lymph node is confirmed microscopically, a negative prognosis may be expected because it is likely that the cancer has spread to the distal lymph node. In addition, inadequate resection of the lymphatic or 14v lymph node adjacent to the 14v lymph node in the absence of evidence of metastasis of the 14v lymph node under microscopic examination indicates that cancer may spread even after curative surgery, To prevent cancer metastasis.
Minimum Age: 19 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The Catholic University of Korea, Incheon St. Mary'S Hospital, Incheon, Bupyeong-gu, Korea, Republic of
Dongnam Inst. of Radiological & Medical Sciences, Busan, Gijang-gun, Korea, Republic of
Gyeongsang national university hospital, Gyeongsang, Gingu-si, Korea, Republic of
National Cancer Center, Gyeonggi-do, Goyang-si, Korea, Republic of
catholic university of korea,Seoul ST. Mary's Hospital., Seocho, Seoul, Korea, Republic of
Severance Hospital, Seoul, Sincon, Korea, Republic of
Asan Medical Center, Seoul, Songpa-gu, Korea, Republic of
A JOU University medical center, Gyeonggi-do, Suwon-si, Korea, Republic of
Pusan National University Yangsan Hospital, Gyeongsang, Yangsan-si, Korea, Republic of
Gyeongsang National University Changwon hospital, Changwon, , Korea, Republic of
Dankook University Hospital, Cheonan, , Korea, Republic of
The CATHOLIC University of KOREA, INCHEON ST.MARY's hospital, Incheon, , Korea, Republic of
Name: HONG MAN YOON, MD
Affiliation: National Cancer Center
Role: PRINCIPAL_INVESTIGATOR