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Spots Global Cancer Trial Database for Olanzapine Improves the Chemotherapy Tolerance of Advanced Gastric Cancer

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Trial Identification

Brief Title: Olanzapine Improves the Chemotherapy Tolerance of Advanced Gastric Cancer

Official Title: Olanzapine Improves the Chemotherapy Tolerance of Advanced Gastric Cancer: a Prospective Randomized Controlled Phase II Clinical Study

Study ID: NCT03575637

Conditions

Gastric Cancer

Interventions

Olanzapine

Study Description

Brief Summary: To explore whether adding olanzapine to paclitaxel chemotherapy could improve chemotherapy tolerance and improve patient quality of life and prolong treatment failure time (TTF) in advanced gastric cancer after failure of first-line chemotherapy. This is a multi-center prospective randomized controlled open clinical study. Patients will formally be enrolled after they had been screened and signed informed consent. Baseline examinations will be started after entry into the group. Those who meet the criteria for inclusion and exclusion were dynamically randomized at 1: 1. The experimental group will receive olanzapine and paclitaxel until treatment failure and the control group will receive paclitaxel until treatment failure.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Peking University Cancer Hospital & Institute, Beijing, , China

Contact Details

Name: Shen Lin

Affiliation: Peking University Cancer Hospital & Institute

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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