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Spots Global Cancer Trial Database for AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

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Trial Identification

Brief Title: AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

Official Title: A Phase III Multi-center, Open-label, Sponsor-blinded, Randomized Study of AZD0901 Monotherapy Compared With Investigator's Choice of Therapy in Second- or Later-Line Adult Participants With Advanced/Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

Study ID: NCT06346392

Study Description

Brief Summary: The purpose of this study is to measure the efficacy and safety of AZD0901 compared to Investigator's choice of therapy as 2L+ treatment for participants with advanced or metastatic gastric or GEJ adenocarcinoma expressing CLDN18.2.

Detailed Description: This is a Phase III, multi-center, open-label, sponsor-blinded, randomized, global study to assess the efficacy and safety of AZD0901 compared to Investigator's choice of therapy as the 2L+ treatment for participants with advanced or metastatic gastric or GEJ adenocarcinoma expressing CLDN18.2, and the clinical performance of the investigational IVD. As part of this combined approach, the efficacy analyses from this study will also provide the basis to evaluate the clinical performance of Ventana CLDN18.2 assay as an IVD device for the identification of patients with advanced or metastatic gastric or GEJ adenocarcinoma expressing CLDN18.2 who may benefit from AZD0901.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Research Site, Birmingham, Alabama, United States

Research Site, Mobile, Alabama, United States

Research Site, Tucson, Arizona, United States

Research Site, Duarte, California, United States

Research Site, Fullerton, California, United States

Research Site, Los Angeles, California, United States

Research Site, Los Angeles, California, United States

Research Site, Santa Rosa, California, United States

Research Site, Washington, District of Columbia, United States

Research Site, Hollywood, Florida, United States

Research Site, Orlando, Florida, United States

Research Site, Atlanta, Georgia, United States

Research Site, Marietta, Georgia, United States

Research Site, Boise, Idaho, United States

Research Site, Lexington, Kentucky, United States

Research Site, Baltimore, Maryland, United States

Research Site, Boston, Massachusetts, United States

Research Site, Ann Arbor, Michigan, United States

Research Site, Kansas City, Missouri, United States

Research Site, Saint Louis, Missouri, United States

Research Site, Saint Louis, Missouri, United States

Research Site, Mineola, New York, United States

Research Site, New York, New York, United States

Research Site, New York, New York, United States

Research Site, New York, New York, United States

Research Site, Cincinnati, Ohio, United States

Research Site, Portland, Oregon, United States

Research Site, Philadelphia, Pennsylvania, United States

Research Site, Charlottesville, Virginia, United States

Research Site, Olympia, Washington, United States

Research Site, Seattle, Washington, United States

Research Site, Calgary, Alberta, Canada

Research Site, Barrie, Ontario, Canada

Research Site, London, Ontario, Canada

Research Site, North York, Ontario, Canada

Research Site, Ottawa, Ontario, Canada

Research Site, Toronto, Ontario, Canada

Research Site, Montreal, Quebec, Canada

Research Site, Beijing, , China

Research Site, Changsha, , China

Research Site, Chengdu, , China

Research Site, Chengdu, , China

Research Site, Fuzhou City, , China

Research Site, Fuzhou, , China

Research Site, Guangzhou, , China

Research Site, Guangzhou, , China

Research Site, Guangzhou, , China

Research Site, Guangzhou, , China

Research Site, Hangzhou, , China

Research Site, Hangzhou, , China

Research Site, Harbin, , China

Research Site, Hefei, , China

Research Site, Jinan, , China

Research Site, Jining, , China

Research Site, Lanzhou, , China

Research Site, Lishui, , China

Research Site, Luoyang, , China

Research Site, Nanjing, , China

Research Site, Nanjing, , China

Research Site, Qingdao, , China

Research Site, Shanghai, , China

Research Site, Shanghai, , China

Research Site, Shanghai, , China

Research Site, Shenyang, , China

Research Site, Shijiazhuang, , China

Research Site, Suzhou, , China

Research Site, Tianjin, , China

Research Site, Urumqi, , China

Research Site, Wuhan, , China

Research Site, Wuhan, , China

Research Site, Xi'an, , China

Research Site, Yinchuan, , China

Research Site, Zhengzhou, , China

Research Site, Besançon Cedex, , France

Research Site, Brest, , France

Research Site, Lille, , France

Research Site, Lyon, , France

Research Site, Nantes, , France

Research Site, PARIS Cedex 12, , France

Research Site, Poitiers, , France

Research Site, Berlin, , Germany

Research Site, Berlin, , Germany

Research Site, Dresden, , Germany

Research Site, Essen, , Germany

Research Site, Frankfurt, , Germany

Research Site, Göttingen, , Germany

Research Site, Hamburg, , Germany

Research Site, Heidelberg, , Germany

Research Site, Heilbronn, , Germany

Research Site, Leipzig, , Germany

Research Site, Mainz, , Germany

Research Site, Marburg, , Germany

Research Site, Moers, , Germany

Research Site, München, , Germany

Research Site, Hong Kong, , Hong Kong

Research Site, Hong Kong, , Hong Kong

Research Site, Ahmedabad, , India

Research Site, Bengaluru, , India

Research Site, Hyderabad, , India

Research Site, Mumbai, , India

Research Site, New Delhi, , India

Research Site, Florence, , Italy

Research Site, Milano, , Italy

Research Site, Milan, , Italy

Research Site, Modena, , Italy

Research Site, Napoli, , Italy

Research Site, Padova, , Italy

Research Site, Pisa, , Italy

Research Site, Vicenza, , Italy

Research Site, Kashiwa, , Japan

Research Site, Tokyo, , Japan

Research Site, Gdańsk, , Poland

Research Site, Katowice, , Poland

Research Site, Kraków, , Poland

Research Site, Lublin, , Poland

Research Site, Szczecin, , Poland

Research Site, Tomaszów Mazowiecki, , Poland

Research Site, Warszawa, , Poland

Research Site, Barcelona, , Spain

Research Site, Barcelona, , Spain

Research Site, Madrid, , Spain

Research Site, Madrid, , Spain

Research Site, Orense, , Spain

Research Site, Santander, , Spain

Research Site, Sevilla, , Spain

Research Site, Bern, , Switzerland

Research Site, Genève 14, , Switzerland

Research Site, Lausanne, , Switzerland

Research Site, Zürich, , Switzerland

Research Site, Kaohsiung, , Taiwan

Research Site, Kaohsiung, , Taiwan

Research Site, Taichung, , Taiwan

Research Site, Tainan, , Taiwan

Research Site, Taipei, , Taiwan

Research Site, Taipei, , Taiwan

Research Site, Taoyuan, , Taiwan

Research Site, Bangkok, , Thailand

Research Site, Dusit, , Thailand

Research Site, Hat Yai, , Thailand

Research Site, Khon-Kaen, , Thailand

Research Site, Cambridge, , United Kingdom

Research Site, London, , United Kingdom

Research Site, London, , United Kingdom

Research Site, Manchester, , United Kingdom

Research Site, Oxford, , United Kingdom

Research Site, Taunton, , United Kingdom

Research Site, Hanoi, , Vietnam

Research Site, Ho Chi Minh city, , Vietnam

Research Site, Ho Chi Minh, , Vietnam

Research Site, Vinh, , Vietnam

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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