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Brief Title: A Phase 1 Dose Escalation Trial of ASG-5ME in Pancreatic or Gastric Adenocarcinoma
Official Title: A Phase 1, Open-Label, Dose Escalation Study of ASG-5ME in Patients With Pancreatic or Gastric Adenocarcinoma
Study ID: NCT01166490
Brief Summary: This is a phase 1, open-label, dose-escalation clinical trial to evaluate the safety and tolerability of ASG-5ME and identify the maximum tolerated dose in patients with pathologically confirmed metastatic pancreatic adenocarcinoma, and to evaluate safety and tolerability in patients with relapsed or refractory gastric adenocarcinoma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
TGen Clinical Research Service at Scottsdale Healthcare, Scottsdale, Arizona, United States
University of California at San Francisco, San Francisco, California, United States
University of Chicago, Chicago, Illinois, United States
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
Texas Oncology - Baylor Sammons Cancer Center, Dallas, Texas, United States
Texas Oncology - Tyler, Tyler, Texas, United States
Seattle Cancer Care Alliance / University of Washington, Seattle, Washington, United States
Name: Nancy Whiting, PharmD, BCOP
Affiliation: Seagen Inc.
Role: STUDY_DIRECTOR