Spots Global Cancer Trial Database for Assessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer
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Trial Identification
Brief Title: Assessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer
Official Title: A Randomized, Double-blind, Placebo-controlled, Phase III Study of Neoadjuvant-Adjuvant Durvalumab and FLOT Chemotherapy Followed by Adjuvant Durvalumab in Patients With Resectable Gastric and Gastroesophageal Junction Cancer (GC/GEJC)
Study ID: NCT04592913
Study Description
Brief Summary: This is a Global Study of Neoadjuvant-Adjuvant Durvalumab or Placebo and FLOT Chemotherapy Followed by Adjuvant Durvalumab or Placebo in Patients with Resectable Gastric and Gastroesophageal Cancer (GC/GEJC) (MATTERHORN).
Detailed Description: This study investigates treatment of durvalumab or placebo therapy combined with FLOT chemotherapy (flurouroacil + leucovorin + oxaliplatin + docetaxel) given before surgery (neoadjuvant) and durvalumab or placebo therapy combined with FLOT chemotherapy after surgery (adjuvant), will work and be safe for the treatment of resectable (removable by surgery) gastric or gastroesophageal cancer, and also to better understand the studied disease and associated health problems.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Research Site, Duarte, California, United States
Research Site, Los Angeles, California, United States
Research Site, Los Angeles, California, United States
Research Site, Sylmar, California, United States
Research Site, Saint Petersburg, Florida, United States
Research Site, Tallahassee, Florida, United States
Research Site, West Palm Beach, Florida, United States
Research Site, Fort Wayne, Indiana, United States
Research Site, Louisville, Kentucky, United States
Research Site, Boston, Massachusetts, United States
Research Site, New York, New York, United States
Research Site, Rochester, New York, United States
Research Site, Nashville, Tennessee, United States
Research Site, Dallas, Texas, United States
Research Site, Lancaster, Texas, United States
Research Site, Seattle, Washington, United States
Research Site, Buenos Aires, , Argentina
Research Site, Buenos Aires, , Argentina
Research Site, Ciudad Autonoma Buenos Aires, , Argentina
Research Site, Ciudad de Buenos Aires, , Argentina
Research Site, Rosario, , Argentina
Research Site, Rosario, , Argentina
Research Site, Charleroi, , Belgium
Research Site, Edegem, , Belgium
Research Site, Leuven, , Belgium
Research Site, Liège, , Belgium
Research Site, Roeselare, , Belgium
Research Site, Barretos, , Brazil
Research Site, Natal, , Brazil
Research Site, Porto Alegre, , Brazil
Research Site, Porto Alegre, , Brazil
Research Site, Rio de Janeiro, , Brazil
Research Site, São José do Rio Preto, , Brazil
Research Site, São Paulo, , Brazil
Research Site, Edmonton, Alberta, Canada
Research Site, North York, Ontario, Canada
Research Site, Oshawa, Ontario, Canada
Research Site, Toronto, Ontario, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Montreal, , Canada
Research Site, La Serena, , Chile
Research Site, Santiago, , Chile
Research Site, Santiago, , Chile
Research Site, Talca, , Chile
Research Site, Temuco, , Chile
Research Site, Temuco, , Chile
Research Site, Aalborg, , Denmark
Research Site, København Ø, , Denmark
Research Site, Odense C, , Denmark
Research Site, Avignon, , France
Research Site, Besançon Cedex, , France
Research Site, Brest Cedex, , France
Research Site, Dijon, , France
Research Site, Lyon, , France
Research Site, Montpellier, , France
Research Site, Nantes, , France
Research Site, Nice, , France
Research Site, Paris cedex 10, , France
Research Site, Paris cedex 15, , France
Research Site, Paris, , France
Research Site, Rennes Cedex 9, , France
Research Site, Berlin, , Germany
Research Site, Dresden, , Germany
Research Site, Frankfurt, , Germany
Research Site, Hamburg, , Germany
Research Site, Hamburg, , Germany
Research Site, Heidelberg, , Germany
Research Site, Heilbronn, , Germany
Research Site, Jena, , Germany
Research Site, Mainz Am Rhein, , Germany
Research Site, München, , Germany
Research Site, Schweinfurt, , Germany
Research Site, Tübingen, , Germany
Research Site, Budapest, , Hungary
Research Site, Győr, , Hungary
Research Site, Kecskemét, , Hungary
Research Site, Szekszárd, , Hungary
Research Site, Szolnok, , Hungary
Research Site, Chuo-ku, , Japan
Research Site, Hidaka-shi, , Japan
Research Site, Hirakata-shi, , Japan
Research Site, Hiroshima-shi, , Japan
Research Site, Kashiwa, , Japan
Research Site, Kitaadachi-gun, , Japan
Research Site, Kochi-shi, , Japan
Research Site, Kurume-shi, , Japan
Research Site, Nagoya-shi, , Japan
Research Site, Niigata-shi, , Japan
Research Site, Ogaki-shi, , Japan
Research Site, Osaka-shi, , Japan
Research Site, Osaka-shi, , Japan
Research Site, Suita-shi, , Japan
Research Site, Sunto-gun, , Japan
Research Site, Tokyo, , Japan
Research Site, Toyoake-shi, , Japan
Research Site, Wakayama-shi, , Japan
Research Site, Yokohama-shi, , Japan
Research Site, Hwasun-gun, , Korea, Republic of
Research Site, Seongnam-si, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Amsterdam, , Netherlands
Research Site, Eindhoven, , Netherlands
Research Site, Rotterdam, , Netherlands
Research Site, Bellavista, , Peru
Research Site, Lima, , Peru
Research Site, Lima, , Peru
Research Site, Lima, , Peru
Research Site, San Isidro, , Peru
Research Site, Bialystok, , Poland
Research Site, Gdańsk, , Poland
Research Site, Kraków, , Poland
Research Site, Poznan, , Poland
Research Site, Poznan, , Poland
Research Site, Warszawa, , Poland
Research Site, Warszawa, , Poland
Research Site, Łódź, , Poland
Research Site, Moscow, , Russian Federation
Research Site, Moscow, , Russian Federation
Research Site, Moscow, , Russian Federation
Research Site, Novosibirsk, , Russian Federation
Research Site, Obninsk, , Russian Federation
Research Site, Saint-Petersburg, , Russian Federation
Research Site, Barcelona, , Spain
Research Site, Barcelona, , Spain
Research Site, Barcelona, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Málaga, , Spain
Research Site, Ourense, , Spain
Research Site, Santander, , Spain
Research Site, Sevilla, , Spain
Research Site, Valencia, , Spain
Research Site, Kaohsiung, , Taiwan
Research Site, Taichung, , Taiwan
Research Site, Tainan City, , Taiwan
Research Site, Taipei, , Taiwan
Research Site, Taipei, , Taiwan
Research Site, Taoyuan City, , Taiwan
Research Site, Adana, , Turkey
Research Site, Ankara, , Turkey
Research Site, Erzurum, , Turkey
Research Site, Istanbul, , Turkey
Research Site, İstanbul, , Turkey
Research Site, Samsun, , Turkey
Research Site, Cambridge, , United Kingdom
Research Site, Dundee, , United Kingdom
Research Site, Glasgow, , United Kingdom
Research Site, Leicester, , United Kingdom
Research Site, London, , United Kingdom
Research Site, Manchester, , United Kingdom
Research Site, Oxford, , United Kingdom
Research Site, Surrey, , United Kingdom
Contact Details
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