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Brief Title: Imatinib TDM in GIST
Official Title: A Phase 2 Study of Imatinib Therapeutic Drug Monitoring in Gastrointestinal Stromal Tumor
Study ID: NCT05493215
Brief Summary: Imatinib can lead to long recurrence free survival in patients diagnosed with gastrointestinal stromal tumors (GIST); however side effects can significantly hinder quality of life for our patients. This study will use therapeutic drug monitoring to improve quality of life and symptoms and assess how many patients maintain therapeutic levels. Free drug levels and pharmokinetics of imatinib will also be monitored.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Markey Cancer Center, Lexington, Kentucky, United States
Name: Reema Patel, MD
Affiliation: University of Kentucky
Role: PRINCIPAL_INVESTIGATOR