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Spots Global Cancer Trial Database for Avastin/Temozolomide/Irinotecan for Unresectable/Multifocal Glioblastoma Multiforme

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Avastin/Temozolomide/Irinotecan for Unresectable/Multifocal Glioblastoma Multiforme

Official Title: Avastin in Combination With Temozolomide and Irinotecan for Unresectable or Multifocal Glioblastoma Multiformes and Gliosarcomas

Study ID: NCT00979017

Study Description

Brief Summary: The primary objective of the study is to determine the efficacy of Avastin in combination with temozolomide and irinotecan in terms of response rate. The secondary objectives are to describe the overall and progression-free survivals of unresectable patients treated with upfront Avastin, temozolomide and irinotecan and to assess the safety of Avastin, temozolomide and irinotecan in unresectable glioblastoma patients. This is a phase II study with the combination of Avastin, temozolomide and irinotecan for unresectable or multifocal World Health Organization (WHO) grade IV malignant glioma patients. Patients will receive up to four cycles of Avastin, temozolomide and irinotecan. Approximately 41 subjects will take part in this study at Duke.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

The Preston Robert Tisch Brain Tumor Center at Duke University Medical Center, Durham, North Carolina, United States

Contact Details

Name: Katherine B Peters, MD, PhD

Affiliation: Duke University

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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