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Spots Global Cancer Trial Database for A Phase 2b Clinical Study With a Combination Immunotherapy in Newly Diagnosed Patients With Glioblastoma

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Trial Identification

Brief Title: A Phase 2b Clinical Study With a Combination Immunotherapy in Newly Diagnosed Patients With Glioblastoma

Official Title: A Randomized, Multicenter, Double-Blind, Placebo-Controlled, Phase 2b Study to Assess the Safety and Efficacy of IGV-001, an Autologous Cell Immunotherapy With Antisense Oligonucleotide (IMV-001) Targeting IGF-1R, in Newly Diagnosed Patients With Glioblastoma

Study ID: NCT04485949

Conditions

Glioblastoma

Study Description

Brief Summary: The purpose of this study is to assess progression-free survival (PFS) and overall survival (OS) in newly diagnosed Glioblastoma (GBM) participants treated with IGV-001 as compared with placebo.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Mayo Clinic - Jacksonville, Jacksonville, Florida, United States

Tufts Medical Center, Boston, Massachusetts, United States

Henry Ford Health System, Detroit, Michigan, United States

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, United States

John Theurer Cancer Center At Hackensack UMC, Hackensack, New Jersey, United States

Jersey Shore University Medical Center, Neptune, New Jersey, United States

Montefiore Medical Center, Bronx, New York, United States

Northwell Health at North Shore University Hospital, Manhasset, New York, United States

David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York, New York, United States

Icahn School of Medicine at Mount Sinai, New York, New York, United States

Columbia University Medical Center, New York, New York, United States

Weill Cornell Medicine, New York, New York, United States

Lenox Hill Hospital, New York, New York, United States

Westchester Medical Center, Valhalla, New York, United States

University of North Carolina (UNC) - Chapel Hill, Chapel Hill, North Carolina, United States

UC Health, Cincinnati, Ohio, United States

The Ohio State University (OSU) Wexner Medical Center, Columbus, Ohio, United States

The Pennsylvania State University (Penn State) Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States

Thomas Jefferson University, Philadelphia, Pennsylvania, United States

University of Pennsylvania, Philadelphia, Pennsylvania, United States

Rhode Island Hospital, Providence, Rhode Island, United States

West Virginia University, Morgantown, West Virginia, United States

University of Wisconsin - Madison, Madison, Wisconsin, United States

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

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