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Spots Global Cancer Trial Database for A Study of the Safety and Pharmacokinetics of BRCX014 in Patients With Glioblastoma

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Trial Identification

Brief Title: A Study of the Safety and Pharmacokinetics of BRCX014 in Patients With Glioblastoma

Official Title: A Phase I Study of BRCX014 to Investigate Dose-Ranging Safety and Pharmacokinetics in Adults With Glioblastoma (GBM) and Non-Methylated MGMT Gene Status

Study ID: NCT03687034

Conditions

Glioblastoma

Interventions

Temozolomide
Optune

Study Description

Brief Summary: An Open-Label, Multi-Center Study to Assess the Safety and Pharmacokinetics of BRCX014 Combined with Standard-of-Care Treatment in Subjects with Glioblastoma

Detailed Description: Several studies have shown a possible anti-tumor role for cannabinoids by modulating cell signaling pathways, inhibiting angiogenesis, inducing apoptosis, and overcoming chemotherapy resistance. The investigators seek to demonstrate the safety profile of BRCX014, a cannabinoid formulation, when given to glioblastoma patients in conjunction with standard-of-care therapy.

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Contact Details

Name: Nicholas Avgeropoulos, MD

Affiliation: Orlando Health / UF Health Cancer Center

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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