Spots Global Cancer Trial Database for Tolerance and Pharmacokinetic Study of Chlorogenic Acid to Advanced Glioblastoma
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Trial Identification
Brief Title: Tolerance and Pharmacokinetic Study of Chlorogenic Acid to Advanced Glioblastoma
Official Title: Phase 1 Trial of Tolerance and Pharmacokinetic of Chlorogenic Acid for Injection in the Advanced Glioblastoma Patients
Study ID: NCT02728349
Conditions
Interventions
Study Description
Brief Summary: The purpose of this study: Determining the Maximum Tolerated Dose (MTD), Dose-Limiting Toxicity (DLT), pharmacokinetics characteristic, and dosage regimen of phase II/III of Chlorogenic acid for injection in the advanced Glioblastoma Patients ;
Detailed Description: 1. Investigate the tolerance of Chlorogenic acid for injection in human body, determine the Maximum Tolerated Dose (MTD) and Dose-Limiting Toxicity (DLT) of Chlorogenic acid for injection in the advanced Glioblastoma Patients ; 2. Determine the human pharmacokinetics characteristic of Chlorogenic acid for injection; 3. Preliminary observation the effectiveness and effective dose; 4. Provide the basis for the dosage regimen of phase II/III.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Beijing Shijitan Hospital,Capital Medical University, Beijing, , China
Contact Details
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