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Spots Global Cancer Trial Database for A Phase 3, Pivotal Trial of VB-111 Plus Bevacizumab vs. Bevacizumab in Patients With Recurrent Glioblastoma (GLOBE)

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Trial Identification

Brief Title: A Phase 3, Pivotal Trial of VB-111 Plus Bevacizumab vs. Bevacizumab in Patients With Recurrent Glioblastoma (GLOBE)

Official Title: A Phase 3, Randomized, Controlled, Double-Arm, Open-Label, Multi-center Study of VB-111 Combined With Bevacizumab vs. Bevacizumab Monotherapy in Patients With Recurrent Glioblastoma

Study ID: NCT02511405

Conditions

Glioblastoma

Study Description

Brief Summary: The purpose of this pivotal, phase 3, randomized, multicenter study is to compare VB-111 plus bevacizumab to bevacizumab in adult patients with recurrent Glioblastoma.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Alabama, Birmingham, Alabama, United States

Highlands Oncology Group, Rogers, Arizona, United States

University of California Irvine Medical Center, Irvine, California, United States

University of California Los Angeles, Los Angeles, California, United States

The Center for Cancer Prevention and Treatment, Orangevale, California, United States

Kaiser Permanente - Redwood City Medical Center, Redwood City, California, United States

University of California, San Diego, California, United States

University of California San Francisco, San Francisco, California, United States

Stanford University, Stanford, California, United States

Colorado Neurological Institute, Denver, Colorado, United States

The George Washington University Medical Faculty Associates, Washington, District of Columbia, United States

University of Florida Preston A. Wells, Jr. Center for Brain Tumor Therapy, Gainesville, Florida, United States

Orlando Health, Orlando, Florida, United States

Piedmont Physicians Neuro-Oncology, Atlanta, Georgia, United States

Northwestern University, Chicago, Illinois, United States

The University of Chicago, Chicago, Illinois, United States

University of Kansas Medical Center, Kansas City, Kansas, United States

University of Kentucky, Lexington, Kentucky, United States

University of Louisville, Louisville, Kentucky, United States

Louisiana State University Health Science Center, Shreveport, Louisiana, United States

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

Dana Farber Cancer Institute, Boston, Massachusetts, United States

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States

Henry Ford Health System, Detroit, Michigan, United States

Metro-MN Community Oncology Research Consortium, Minneapolis, Minnesota, United States

Washington University School of Medicine, Saint Louis, Missouri, United States

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, United States

Dent Neurosciences Research Center, Amherst, New York, United States

North Shore University Hospital, Lake Success, New York, United States

Columbia University Medical Center, New York, New York, United States

Derald H. Ruttenberg Treatment Center, New York, New York, United States

University of Rochester Medical Center, Rochester, New York, United States

Stony Brook University, Neurology Associates of Stony Brook, Stony Brook, New York, United States

SUNY Upstate Medical University, Syracuse, New York, United States

University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States

Wake Forest Baptist Medical Center, Winston-Salem, North Carolina, United States

Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, United States

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States

Texas Oncology-Austin Midtown, Austin, Texas, United States

Baylor Health Neuro-Oncology Associates, Dallas, Texas, United States

University of Texas Southwestern Medical Center, Dallas, Texas, United States

: University of Texas, HSC, Houston, Texas, United States

MD Anderson, Houston, Texas, United States

UTHSCSA, San Antonio, Texas, United States

Huntsman Cancer Institute at The University of Utah, Salt Lake City, Utah, United States

University of Virginia, Charlottesville, Virginia, United States

Swedish Medical Center, Seattle, Washington, United States

University of Wisconsin, Madison, Wisconsin, United States

Tom Baker Cancer Centre, Calgary, Alberta, Canada

London Health Sciences Centre, London, Ontario, Canada

Ottawa Hospital, Ottawa, Ontario, Canada

Sunnybrook Health Science Centre, Toronto, Ontario, Canada

Rambam Medical Center, Haifa, , Israel

Hadassah Medical Center, Jerusalem, , Israel

Rabin Medical Center, Petach Tikvah, , Israel

Chaim Sheba Medical Center, Ramat Gan, , Israel

Tel Aviv Sourasky Medical Center, Tel Aviv, , Israel

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

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