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Spots Global Cancer Trial Database for A Trial of Enzastaurin Plus Temozolomide During and Following Radiation Therapy in Patients With Newly Diagnosed Glioblastoma With or Without the Novel Genomic Biomarker, DGM1

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Trial Identification

Brief Title: A Trial of Enzastaurin Plus Temozolomide During and Following Radiation Therapy in Patients With Newly Diagnosed Glioblastoma With or Without the Novel Genomic Biomarker, DGM1

Official Title: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of Enzastaurin Added to Temozolomide During and Following Radiation Therapy in Newly Diagnosed Glioblastoma Patients Who Possess the Novel Genomic Biomarker DGM1

Study ID: NCT03776071

Conditions

Glioblastoma

Study Description

Brief Summary: This study will be conducted as a randomized, double-blind, placebo-controlled, multi-center Phase 3 study. Approximately 300 subjects with newly diagnosed glioblastoma who meet all eligibility criteria will be enrolled.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Alabama at Birmingham, Birmingham, Alabama, United States

Barrow Neurological Institute, Phoenix, Arizona, United States

Mayo Clinic - Arizona, Scottsdale, Arizona, United States

City of Hope Comprehensive Cancer Center - Duarte, Duarte, California, United States

University of California San Diego Moores Cancer Center, La Jolla, California, United States

Cedars-Sinai Medical Center, Los Angeles, California, United States

University of California Irvine Health Chao Family Comprehensive Cancer Center, Orange, California, United States

The University of Southern California, Pasadena, California, United States

University of California San Francisco Helen Diller Family Comprehensive CA Ctr, San Francisco, California, United States

University of Colorado Hospital Anschutz Cancer Pavilion, Aurora, Colorado, United States

Blue Sky Neurology, Englewood, Colorado, United States

Smilow Cancer Hospital - New Haven, New Haven, Connecticut, United States

Lynn Cancer Institute, Boca Raton, Florida, United States

Mayo Clinic - Jacksonville, Jacksonville, Florida, United States

Sylvester Comprehensive Cancer Center, Miami, Florida, United States

Miami Cancer Institute, Miami, Florida, United States

Moffitt Cancer Center, Tampa, Florida, United States

Winship Cancer Institute of Emory University, Atlanta, Georgia, United States

Rush University Medical Center, Chicago, Illinois, United States

University of Kentucky Markey Cancer Center, Lexington, Kentucky, United States

Norton Cancer Institute - Multidisciplinary Clinic, Louisville, Kentucky, United States

University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, United States

Henry Ford Health System, Detroit, Michigan, United States

John Nasseff Neuroscience Institute, Minneapolis, Minnesota, United States

Masonic Cancer Center, Minneapolis, Minnesota, United States

Mayo Clinic - Rochester, Rochester, Minnesota, United States

Washington University School of Medicine Center for Advanced Medicine, Saint Louis, Missouri, United States

Hackensack Meridian Health - JFK Medical Center, Edison, New Jersey, United States

New York University Medical Oncology Associates, New York, New York, United States

Icahn School of Medicine at Mount Sinai, New York, New York, United States

New York - Presbyterian - Weill Cornell Medical Center, New York, New York, United States

Messino Cancer Centers, Asheville, North Carolina, United States

The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States

Wake Forest Baptist Health - Comprehensive Cancer Center, Winston-Salem, North Carolina, United States

The Ohio State University - The James Cancer Hospital and Solove Research Institute, Columbus, Ohio, United States

Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States

Penn Medicine - Perelman Center for Advanced Medicine, Philadelphia, Pennsylvania, United States

University of Pittsburgh Medical Center - Hillman Cancer Center, Pittsburgh, Pennsylvania, United States

SCRI - Tennessee Oncology - Nashville - Centennial, Nashville, Tennessee, United States

Vanderbilt - Ingram Cancer Center, Nashville, Tennessee, United States

Austin Cancer Center - Park St. David's, Austin, Texas, United States

Baylor University Medical Center, Dallas, Texas, United States

Lynn Cancer Institute, Houston, Texas, United States

University of Texas Health Science Center at Houston (UT Health), Houston, Texas, United States

Mays Cancer Center, San Antonio, Texas, United States

University of Utah, Salt Lake City, Utah, United States

Seattle Cancer Care Alliance, Seattle, Washington, United States

Cross Cancer Institute, Edmonton, Alberta, Canada

British Columbia Cancer Agency - Abbotsford, Abbotsford, British Columbia, Canada

British Columbia Cancer Agency - Victoria, Victoria, British Columbia, Canada

The Ottawa Hospital - General Campus, Ottawa, Ontario, Canada

Hôpital Fleurimont, Sherbrooke, Quebec, Canada

Saskatoon Cancer Center, Saskatoon, Saskatchewan, Canada

First Affiliated Hospital of USTC - Anhui Provincial Hospital, Hefei, Anhui, China

Beijing Tian Tan Hospital, Capital Medical University, Beijing, Beijing, China

Sanbo Brain Hospital, Capital Medical University, Beijing, Beijing, China

Peking Union Medical College Hospital, Beijing, Beijing, China

Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, China

Shenzhen Second People's Hospital, Shenzhen, Guangdong, China

Tongji Hospital, Wuhan, Hubei, China

Shengjing Hospital - Nanhu Campus, Shenyang, Liaoning, China

Tangdu Hospital, Xian, Shaanxi, China

Huashan Hospital Affiliated to Fudan University, Shanghai, Shanghai, China

Tianjin Huanhu Hospital, Jinnan, Tianjin, China

General Hospital of Tianjin Medical University, Tianjin, Tianjin, China

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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