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Brief Title: Memantine for Recurrent Glioblastoma
Official Title: A Phase II Study of Memantine in the Treatment of Recurrent Glioblastoma
Study ID: NCT01260467
Brief Summary: The purpose of this study is to determine if a medication called memantine is effective in treating glioblastoma. Memantine targets a specific receptor, called a glutamate receptor, which is thought to be involved in the growth of brain tumors. It has previously been studied for other types of conditions, such as Alzheimer's disease, but it has not yet been evaluated in the treatment of brain tumors. The investigators will also be determining how common it is for patients with brain tumors to have side effects to memantine. Memantine will be taken by mouth twice a day.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Rochester Medical Center, Rochester, New York, United States
Name: Nimish Mohile, MD
Affiliation: University of Rochester
Role: PRINCIPAL_INVESTIGATOR