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Brief Title: Association Between Vitamin D and the Risk of Uterine Fibroids
Official Title: Association Between Vitamin D and the Risk of Uterine Fibroids
Study ID: NCT03586947
Brief Summary: The aim of this randomised clinical trial study is to evaluate whether supplementation with vitamin D could reduce the risk of uterine fibroids in reproductive stage women.
Detailed Description: A total of 1160 hypovitaminosis D patients (12 ng/ml ≤ serum 25-hydroxyvitamin D3 \< 20 ng/ml) without uterine fibroids will be randomly assigned in a ratio of 1:1 to two groups: intervention group and control group. The intervention group will receive 1600 IU/d of vitamin D3; the control group will receive regular follow-up. Patients will be followed up at the same time points for 24 months. The outcome measure is the incidence of uterine fibroids in different groups.
Minimum Age: 35 Years
Eligible Ages: ADULT
Sex: FEMALE
Healthy Volunteers: Yes
The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China