Spots Global Cancer Trial Database for Scalp Cooling in Gynecologic Cancer Patients
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Trial Identification
Brief Title: Scalp Cooling in Gynecologic Cancer Patients
Official Title: The Psychological Impact of Scalp Cooling in Patients Receiving Chemotherapy for Primary Gynecologic Cancers: a Randomised Trial
Study ID: NCT04168242
Study Description
Brief Summary: In gynecologic cancers, many common chemotherapy agents can lead to chemotherapy-induced alopecia. Currently scalp cooling is the most well studied preventive measure. However, its acceptability and its impact on patients' QOL in Asian population is unclear.
Detailed Description: Dynamic scalp cooling system prevents alopecia by inducing vasoconstriction leading to a reduction of scalp blood flow, thus reducing the delivery of cytotoxic drugs to the hair follicles and reducing follicular metabolic activities. One recent meta-analysis included 10 studies showed that the efficacy was 43% in general.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
The University of Hong Kong, Hong Kong, , Hong Kong
Contact Details
Name: Ka Yu Tse
Affiliation: The University of Hong Kong
Role: PRINCIPAL_INVESTIGATOR
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