Spots Global Cancer Trial Database for Identification and Prevention of Pelvic Floor Dysfunction in Gynecologic Cancer Survivors
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Trial Identification
Brief Title: Identification and Prevention of Pelvic Floor Dysfunction in Gynecologic Cancer Survivors
Official Title: Identification and Prevention of Pelvic Floor Dysfunction in Gynecologic Cancer Survivors
Study ID: NCT05769062
Conditions
Interventions
Study Description
Brief Summary: The two goals of this study are to establish a standardized method of assessing the pelvic floor for patients undergoing pelvic radiation and to determine the feasibility of inverse-RT planning using MRI to identify dosimetric constraints of the pelvic floor musculature for use in radiation planning. The investigators hypothesize that an exam-based diagnostic tool will provide more information about the areas of injury related to pelvic radiation than patient-reported outcomes, and could be used in future studies of preventive strategies. An exam-based tool will also allow measurement of the pain dose-response to radiation treatment of specific areas, which could be excluded from radiation fields during treatment planning.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Washington University School of Medicine, Saint Louis, Missouri, United States
Contact Details
Name: Tyler McKinnish, M.D.
Affiliation: Washington University School of Medicine
Role: PRINCIPAL_INVESTIGATOR
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