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Brief Title: An Integrative Multi-Omic Characterization of Head and Neck Carcinogenesis, Progression and Recurrence
Official Title: An Integrative Multi-Omic Characterization of Head and Neck Carcinogenesis, Progression and Recurrence
Study ID: NCT06420219
Brief Summary: This study evaluates the cell and biomarkers associated with the aggressive behavior of cancer.
Detailed Description: PRIMARY OBJECTIVE: I. High-resolution single-cell profiling of Cancer-associated fibroblasts (CAFs) in Human papillomavirus (HPV)+ Oropharyngeal Squamous Cell Carcinoma (OPSCC) and metastatic lymph nodes. OUTLINE: This is an observational study. Patients undergo photography, blood sample collection, tissue collection and have their medical records reviewed on study.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States
Name: Albert Y Han, MD
Affiliation: University of Southern California
Role: PRINCIPAL_INVESTIGATOR