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Brief Title: Study of Magrolimab Combination Therapy in Patients With Head and Neck Squamous Cell Carcinoma
Official Title: A Phase 2 Study of Magrolimab Combination Therapy in Patients With Head and Neck Squamous Cell Carcinoma
Study ID: NCT04854499
Brief Summary: The goals of this clinical study are to learn about the safety, tolerability, dosing and effectiveness of the study drug, magrolimab in combination with other anticancer therapies in patients with head and neck squamous cell carcinoma (HNSCC).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Ironwood Cancer and Research Center, Chandler, Arizona, United States
City of Hope, Duarte, California, United States
UCLA Hematology/Oncology, Los Angeles, California, United States
Stanford Cancer Institute, Palo Alto, California, United States
Torrance Memorial Physician Network - Cancer Care Associates, Redondo Beach, California, United States
Providence Medical Foundation, Santa Rosa, California, United States
Memorial Healthcare System, Hollywood, Florida, United States
Ocala Oncology Center, Ocala, Florida, United States
University Center and Blood Center,LLC., Athens, Georgia, United States
Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, United States
Virginia Piper Cancer Center (Alliant Health, Minneapolis, Minnesota, United States
Washington University of Medicine- Siteman Cancer Center, Saint Louis, Missouri, United States
Astera Cancer Care, East Brunswick, New Jersey, United States
Icahn School of Medicine at Mount Sinai and the Mount Sinai Hospital, New York, New York, United States
New York Cancer and Blood Specialists, Port Jefferson Station, New York, United States
Sanford Roger Maris Cancer Center, Fargo, North Dakota, United States
OU Health Stephenson Cancer Center, Oklahoma City, Oklahoma, United States
Lancaster General Hospital, Lancaster, Pennsylvania, United States
Medical University of South Carolina, Charleston, South Carolina, United States
Avera Cancer Institute, Sioux Falls, South Dakota, United States
MD Anderson Cancer Center, Houston, Texas, United States
Huntsman Cancer Institute, Salt Lake City, Utah, United States
St. Vincent's Hospital Sydney, Darlinghurst, New South Wales, Australia
Macquarie University, Macquarie Park, New South Wales, Australia
Blacktown Hospital, Westmead, New South Wales, Australia
Cairns Hospital, Cairns, Queensland, Australia
University of the Sunshine Coast, Sippy Downs, Queensland, Australia
Princess Alexandra Hospital, Woolloongabba, Queensland, Australia
Austin Health, Heidelberg, Victoria, Australia
Alfred Health, Melbourne, Victoria, Australia
ZiekenhuisNetwerk Antwerpen (ZNA) - Stuivenberg, Antwerpen, , Belgium
Algemeen Ziekenhuis Klina, Brasschaat, , Belgium
UZ Antwerpen, Edegem, , Belgium
Universitaire Ziekenhuis Leuven, Leuven, , Belgium
Centre Hospitalizer De L'Ardenne, Libramont-Chevigny, , Belgium
AZ Sint-Maarten, Mechelen, , Belgium
CHU UCL Namur - Sainte-Elisabeth, Namur, , Belgium
Institut Bergonie, Bordeaux, , France
Centre Georges François Leclerc, Dijon, , France
Centre Léon Bérard, Lyon, , France
Hopital de la Timone, Marseille, , France
Centre de Lutte Contre le Cancer (CLCC) - Centre Antoine Lacassagne (CAL) - Site Est, Nice, , France
Institut Curie, Paris, , France
Hopital Pitie-Salpetriere, Paris, , France
Civils de Lyon-Centre Hopitalier Lyon Sud, Pierre-benite, , France
Hopital Foch, Suresnes, , France
Institut Gustave Roussy, Villejuif, , France
Charite University Medicine, Berlin, , Germany
Universitätsklinikum Bonn, Medizinische Klinik und Poliklinik III, Bonn, , Germany
Universitatsmedizin Gottingen, GÃttingen, , Germany
Kath. Marienkrankenhaus gGmbH, Hamburg, , Germany
Universitäres Krebszentrum Leipzig, Leipzig, , Germany
Technische Universitat Munchen (TUM) - Klinikum Rechts der Isar, Munich, , Germany
Queen Mary Hospital, Hong Kong, , Hong Kong
Princess Margaret Hospital, Lai Chi Kok, , Hong Kong
Azienda Ospedaliero - Universitaria di Bologna - IRCCS, Bologna, , Italy
ASST degli Spedali Civili di Brescia, Brescia, , Italy
Ospedale San Luca Luca, Lucca, , Italy
Fondazione IRCCS Istituto Nazionale Tumori Milano, Milan, , Italy
Azienda Ospedaliero-Universitaria di Modena - Policlinico, Modena, , Italy
Arcispedale Santa Maria Nuova, Reggio Emilia, , Italy
Azienda Ospedaliero - Universitaria Senese, Siena, , Italy
Centrum Onkologii im. Prof. Franciszka Lukaszczyka w Bydgoszczy, Bydgoszcz, , Poland
Narodowy Instytut Onkologii im. M. Sklodowskiej-Curie, Panstwowy Instytut Badawczy, Oddzial x Gliwicach, Gliwice, , Poland
Wielkopolskie Centrum Onkologii im. Marii Sklodowskiej-Curie, Oddzial Onkologii Klinicznej i Immunookologii z Poddoddzialem Dziennym i Izba Przyjec, Poznan, , Poland
Wojewodzki Szpital Specjalistyczny w Siedlcach, Siedlce, , Poland
Narodowy Instytut Onkologii im. M. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy, Klinika Nowotworow Glowy i Szyi, Warsaw, , Poland
Hospital de Braga, Braga, , Portugal
Centro Hospitalar do Algarve, Faro, , Portugal
Hospital CUF Descobertas, Lisboa, , Portugal
Unidade Local de Saude de Matosinhos EPE - Hospital Pedro Hispano SA, Matosinhos, , Portugal
Centro Hospitalar Universitario do Porto, Porto, , Portugal
Instituto Portugues de Oncologia Do Porto Francisco Gentil,E.P.E., Porto, , Portugal
Hospital Universitari Vall d'Hebron, Barcelona, , Spain
Hospital del Mar, Barcelona, , Spain
Hospital De La Santa Creu I Sant Pau, Barcelona, , Spain
Hospital Universitario de Jaen, Jaen, , Spain
Hospital General Universitario Gregorio Maranon, Madrid, , Spain
MD Anderson Cancer Center, Madrid, , Spain
Hospital Universitario La Paz, Madrid, , Spain
Hospital Regional Universitario de Malaga, Malaga, , Spain
Clinica Universidad de Navarra, Pamplona, , Spain
Hospital Universitario Virgen Macarena, Sevilla, , Spain
Hospital Universitario Virgen del Rocio, Sevilla, , Spain
Hospital Universitari i Politecnic La Fe, Valencia, , Spain
Hospital Clínico Universitario de Valencia, Valencia, , Spain
Royal Marsden NHS Foundation Trust, Royal Marsden - Sutton, London, , United Kingdom
Musgrove Park Hospital, Taunton, , United Kingdom
Name: Gilead Study Director
Affiliation: Gilead Sciences
Role: STUDY_DIRECTOR