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Brief Title: NIMRAD (A Randomised Placebo-controlled Trial of Synchronous NIMorazole Versus RADiotherapy Alone in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma Not Suitable for Synchronous Chemotherapy or Cetuximab)
Official Title: A Randomised Placebo-controlled Trial of Synchronous NIMorazole Versus RADiotherapy Alone in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma Not Suitable for Synchronous Chemotherapy or Cetuximab)
Study ID: NCT01950689
Brief Summary: The purpose of this study is to see whether adding Nimorazole to standard radiotherapy benefits patients with locally advanced head and neck squamous cell carcinoma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Cheltenham General Hospital, Cheltenham, Gloucestershire, United Kingdom
Clatterbridge Centre for Oncology, Bebington, Merseyside, United Kingdom
St James' Hospital, Leeds, West Yorkshire, United Kingdom
Belfast City Hospital, Belfast, , United Kingdom
Queen Elizabeth Hospital, Birmingham, , United Kingdom
Bradford Teaching Hospitals NHS Foundation Trust, Bradford, , United Kingdom
Bristol Haematology and Oncology centre, Bristol, , United Kingdom
Addenbrookes Hospital, Cambridge, , United Kingdom
Velindre Cancer Centre, Cardiff, , United Kingdom
University Hospitals Coventry and Warwickshire, Coventry, , United Kingdom
The Beatson West of Scotland Cancer Centre, Glasgow, , United Kingdom
The Royal Surrey County Hospital, Guildford, , United Kingdom
Leicester Royal Infirmary, Leicester, , United Kingdom
University College London Hospital, London, , United Kingdom
The Royal Marsden, London, , United Kingdom
The Christie NHS Foundation Trust, Manchester, , United Kingdom
The James Cook University Hospital, Middlesborough, , United Kingdom
Nottingham University Hospitals, Nottingham, , United Kingdom
Weston Park Hospital, Sheffield, , United Kingdom
Singleton Hospital, Swansea, , United Kingdom
York Hospital, York, , United Kingdom
Name: David Thomson
Affiliation: The Christie NHS Foundation Trust
Role: PRINCIPAL_INVESTIGATOR